Multimodal assessment of estrogen receptor mRNA profiles to quantify estrogen pathway activity in breast tumors

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Multimodal assessment of estrogen receptor mRNA profiles to quantify estrogen pathway activity in breast tumors

Background Molecular markers have transformed our understanding of the heterogeneity of breast cancer and have allowed the identification of genomic profiles of estrogen receptor (ER)-α signaling. However, our understanding of the transcriptional profiles of ER signaling remains inadequate. There...

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Bibliographic Details
Main Authors:	Muthukaruppan, Anita, Lasham, Annette, Woad, Kathryn J., Black, Michael A., Blenkiron, Cherie, Miller, Lance D., Harris, Gavin, McCarthy, Nicole, Findlay, Michael P., Shelling, Andrew N., Print, Cristin G.
Format:	Article
Published:	Elsevier 2017
Subjects:	Breast cancer; ER; ESR1; Gene expression; MCF7; Principal component analysis; RNA
Online Access:	https://eprints.nottingham.ac.uk/37806/

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