Automated electrophysiological and pharmacological evaluation of human pluripotent stem cell-derived cardiomyocytes
Automated planar patch clamp systems are widely used in drug evaluation studies because of their ability to provide accurate, reliable, and reproducible data in a high-throughput manner. Typically, CHO and HEK tumorigenic cell lines overexpressing single ion channels are used since they can be harve...
| Main Authors: | Rajamohan, Divya, Kalra, Spandan, Hoang, Minh Duc, George, Vinoj, Staniforth, Andrew, Russell, Hugh, Yang, Xuebin, Denning, Chris |
|---|---|
| Format: | Article |
| Published: |
MAry Ann Liebert
2016
|
| Online Access: | https://eprints.nottingham.ac.uk/37773/ |
Similar Items
Can human pluripotent stem cell-derived cardiomyocytes advance understanding of muscular dystrophies?
by: Kalra, Spandan, et al.
Published: (2016)
by: Kalra, Spandan, et al.
Published: (2016)
Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform
by: Denning, Chris, et al.
Published: (2016)
by: Denning, Chris, et al.
Published: (2016)
Current status of drug screening and disease modelling in human pluripotent stem cells
by: Rajamohan, Divya, et al.
Published: (2013)
by: Rajamohan, Divya, et al.
Published: (2013)
Exon skipping and gene transfer restore dystrophin expression in human induced pluripotent stem cells-cardiomyocytes harboring DMD mutations
by: Dick, Emily, et al.
Published: (2013)
by: Dick, Emily, et al.
Published: (2013)
Drug-mediated shortening of action potentials in LQTS2 hiPSC-cardiomyocytes
by: Duncan, Gary, et al.
Published: (2017)
by: Duncan, Gary, et al.
Published: (2017)
Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes
by: Matsa, Elena, et al.
Published: (2013)
by: Matsa, Elena, et al.
Published: (2013)
Evaluating human induced pluripotent stem cell-derived cardiomyocytes for commercial drug testing
by: Katili, Puspita Anggraini
Published: (2020)
by: Katili, Puspita Anggraini
Published: (2020)
Establishment of the human cardiac models using gene editing and reprogramming in Human Pluripotent Stem Cells to understand the putative functions of the G-protein coupled receptor kinase 5 polymorphism (GRK5-L41)
by: Hoang, Minh Duc
Published: (2017)
by: Hoang, Minh Duc
Published: (2017)
Engineered human pluripotent stem cell derived cardiomyocyte platforms to detect cardiovascular safety liabilities
by: Firth, Karl
Published: (2017)
by: Firth, Karl
Published: (2017)
Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology
by: Lei, Chon-Lok, et al.
Published: (2017)
by: Lei, Chon-Lok, et al.
Published: (2017)
CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy
by: Mosqueira, Diogo, et al.
Published: (2018)
by: Mosqueira, Diogo, et al.
Published: (2018)
Linking molecular targets to hypertrophic cardiomyopathy using genome-edited human induced pluripotent stem cell cardiomyocytes
by: Bodbin, S.E.
Published: (2022)
by: Bodbin, S.E.
Published: (2022)
A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials microarrays
by: Patel, Asha K., et al.
Published: (2015)
by: Patel, Asha K., et al.
Published: (2015)
Simplified footprint-free Cas9/CRISPR editing of cardiac-associated genes in human pluripotent stem cells
by: Kondrashov, Alexander, et al.
Published: (2018)
by: Kondrashov, Alexander, et al.
Published: (2018)
Dynamic electrophysiological connectomics
by: O'Neill, George C.
Published: (2016)
by: O'Neill, George C.
Published: (2016)
An investigation into the function and mechanism of a GRK5-L41 polymorphism using human pluripotent cell-derived cardiomyocytes
by: Vo, Nguyen T. N.
Published: (2021)
by: Vo, Nguyen T. N.
Published: (2021)
Discovery of a novel polymer for human pluripotent stem cell expansion and multilineage differentiation
by: Celiz, Adam D., et al.
Published: (2015)
by: Celiz, Adam D., et al.
Published: (2015)
Automated Trading System
by: Le, Duc Minh
Published: (2008)
by: Le, Duc Minh
Published: (2008)
Disease modeling hypertrophic cardiomyopathy using CRISPR/Cas9 genome editing technology in human pluripotent stem cell-derived cardiomyocytes
by: Mosqueira, Diogo
Published: (2018)
by: Mosqueira, Diogo
Published: (2018)
Human pluripotent stem cells derived-cardiomyocytes (hPSC-CMs) to assess the impact of drug- and gene-induced changes on cell function
by: Mohd Yusof, Nurul Ain Nasim
Published: (2020)
by: Mohd Yusof, Nurul Ain Nasim
Published: (2020)
Developing an automation-compatible quantitative and functional assay for the assessment of pluripotency
by: Flatt, Luke
Published: (2017)
by: Flatt, Luke
Published: (2017)
Building 3D architectures for cardiomyocytes
by: Turgut, Aylin
Published: (2021)
by: Turgut, Aylin
Published: (2021)
Neural differentiation of human pluripotent stem cells for nontherapeutic applications: Toxicology, pharmacology, and in vitro disease modelling [Review article].
by: Yap, May Shin *, et al.
Published: (2015)
by: Yap, May Shin *, et al.
Published: (2015)
Introduction to advanced electrophysiological testings
by: Dzulkarnain, Ahmad Aidil Arafat
Published: (2015)
by: Dzulkarnain, Ahmad Aidil Arafat
Published: (2015)
Electrophysiological characterisation of central sensitisation in canine spontaneous osteoarthritis
by: Hunt, James Russell, et al.
Published: (2018)
by: Hunt, James Russell, et al.
Published: (2018)
ASIC based recorders of electrophysiological signals
by: Harrison, Andrew
Published: (1995)
by: Harrison, Andrew
Published: (1995)
On the antecedents of an electrophysiological
signature of retrieval mode
by: Williams, Angharad N., et al.
Published: (2016)
by: Williams, Angharad N., et al.
Published: (2016)
Modelling the effect of ischemia on myocardial electrophysiology
by: P. N. A. Nasuha, Mohd Nor, et al.
Published: (2022)
by: P. N. A. Nasuha, Mohd Nor, et al.
Published: (2022)
Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation
by: Dixon, James E., et al.
Published: (2014)
by: Dixon, James E., et al.
Published: (2014)
Dynamics of large-scale electrophysiological networks: a technical review
by: O'Neill, George C., et al.
Published: (2017)
by: O'Neill, George C., et al.
Published: (2017)
Automation and scale-up of human induced pluripotent stem cell models of cardiovascular disease for drug screening
by: Crutchley, James E.B.
Published: (2016)
by: Crutchley, James E.B.
Published: (2016)
Relationships between cortical myeloarchitecture and electrophysiological networks
by: Hunt, Benjamin A. E., et al.
Published: (2016)
by: Hunt, Benjamin A. E., et al.
Published: (2016)
Electrophysiological indices of strategic episodic retrieval processing
by: Dzulkifli, Mariam Adawiah, et al.
Published: (2005)
by: Dzulkifli, Mariam Adawiah, et al.
Published: (2005)
Identification of polymer surface adsorbed proteins implicated in pluripotent human embryonic stem cell expansion
by: Hammad, Moamen, et al.
Published: (2016)
by: Hammad, Moamen, et al.
Published: (2016)
The effects of undernutrition and dexamethasone treatment on cultured rat neonatal cardiomyocytes
by: Austin, Ruth Marie
Published: (2010)
by: Austin, Ruth Marie
Published: (2010)
Measuring temporal, spectral and spatial changes in electrophysiological brain network connectivity
by: Brookes, Matthew Jon, et al.
Published: (2014)
by: Brookes, Matthew Jon, et al.
Published: (2014)
Improving the maturation of human pluripotent stem cell - derived hepatocyte-like cells using an automated-design of experiments approach
by: Fotopoulos, Lazaros
Published: (2019)
by: Fotopoulos, Lazaros
Published: (2019)
Electrophysiological measures of conflict detection and resolution in the Stroop task
by: Coderre, Emily L., et al.
Published: (2011)
by: Coderre, Emily L., et al.
Published: (2011)
Reproducible model development in the Cardiac Electrophysiology Web Lab
by: Daly, Aidan C., et al.
Published: (2018)
by: Daly, Aidan C., et al.
Published: (2018)
USM DAAD SUMMER SCHOOL STRENGTHENS
EXPERTISE IN ELECTROPHYSIOLOGY
by: MPRC, Pusat Media & Perhubungan Awam
Published: (2015)
by: MPRC, Pusat Media & Perhubungan Awam
Published: (2015)
Similar Items
-
Can human pluripotent stem cell-derived cardiomyocytes advance understanding of muscular dystrophies?
by: Kalra, Spandan, et al.
Published: (2016) -
Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform
by: Denning, Chris, et al.
Published: (2016) -
Current status of drug screening and disease modelling in human pluripotent stem cells
by: Rajamohan, Divya, et al.
Published: (2013) -
Exon skipping and gene transfer restore dystrophin expression in human induced pluripotent stem cells-cardiomyocytes harboring DMD mutations
by: Dick, Emily, et al.
Published: (2013) -
Drug-mediated shortening of action potentials in LQTS2 hiPSC-cardiomyocytes
by: Duncan, Gary, et al.
Published: (2017)