3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles

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3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles

We have used three dimensional (3D) extrusion printing to manufacture a multi-active solid dosage form or so called polypill. This contains five compartmentalised drugs with two independently controlled and well-defined release profiles. This polypill demonstrates that complex medication regimes can...

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Bibliographic Details
Main Authors:	Khaled, Shaban A., Burley, Jonathan C., Alexander, Morgan R., Yang, Jing, Roberts, Clive J.
Format:	Article
Published:	Elsevier 2015
Subjects:	3D printing; Polypill; Sustained release; Immediate release; Personalised medicine
Online Access:	https://eprints.nottingham.ac.uk/37750/

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