Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK

Data were extracted from the case records of UK patients admitted with laboratory-confirmed influenza A(H1N1)pdm09. White and non-White patients were characterized by age, sex, socioeconomic status, pandemic wave and indicators of pre-morbid health status. Logistic regression examined differences by...

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Main Authors: Nyland, G.A., McKenzie, B.C., Myles, Puja R., Semple, M.G., Lim, W.S., Openshaw, Peter J.M., Read, R.C., Taylor, B.L., Brett, S.J., Mcmenamin, J., Enstone, J.E., Bannister, B., Nicholson, K.G., Nguyen-Van-Tam, Jonathan
Format: Article
Published: Cambridge University Press 2014
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Online Access:https://eprints.nottingham.ac.uk/37740/
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author Nyland, G.A.
McKenzie, B.C.
Myles, Puja R.
Semple, M.G.
Lim, W.S.
Openshaw, Peter J.M.
Read, R.C.
Taylor, B.L.
Brett, S.J.
Mcmenamin, J.
Enstone, J.E.
Bannister, B.
Nicholson, K.G.
Nguyen-Van-Tam, Jonathan
author_facet Nyland, G.A.
McKenzie, B.C.
Myles, Puja R.
Semple, M.G.
Lim, W.S.
Openshaw, Peter J.M.
Read, R.C.
Taylor, B.L.
Brett, S.J.
Mcmenamin, J.
Enstone, J.E.
Bannister, B.
Nicholson, K.G.
Nguyen-Van-Tam, Jonathan
author_sort Nyland, G.A.
building Nottingham Research Data Repository
collection Online Access
description Data were extracted from the case records of UK patients admitted with laboratory-confirmed influenza A(H1N1)pdm09. White and non-White patients were characterized by age, sex, socioeconomic status, pandemic wave and indicators of pre-morbid health status. Logistic regression examined differences by ethnicity in patient characteristics, care pathway and clinical outcomes; multivariable models controlled for potential confounders. Whites (n = 630) and non-Whites (n = 510) differed by age, socioeconomic status, pandemic wave of admission, pregnancy, recorded obesity, previous and current smoking, and presence of chronic obstructive pulmonary disease. After adjustment for a priori confounders non-Whites were less likely to have received pre-admission antibiotics [adjusted odds ratio (aOR) 0·43, 95% confidence interval (CI) 0·28–0·68, P < 0·001) but more likely to receive antiviral drugs as in-patients (aOR 1·53, 95% CI 1·08–2·18, P = 0·018). However, there were no significant differences by ethnicity in delayed admission, severity at presentation for admission, or likelihood of severe outcome.
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spelling nottingham-377402024-08-15T15:15:47Z https://eprints.nottingham.ac.uk/37740/ Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK Nyland, G.A. McKenzie, B.C. Myles, Puja R. Semple, M.G. Lim, W.S. Openshaw, Peter J.M. Read, R.C. Taylor, B.L. Brett, S.J. Mcmenamin, J. Enstone, J.E. Bannister, B. Nicholson, K.G. Nguyen-Van-Tam, Jonathan Data were extracted from the case records of UK patients admitted with laboratory-confirmed influenza A(H1N1)pdm09. White and non-White patients were characterized by age, sex, socioeconomic status, pandemic wave and indicators of pre-morbid health status. Logistic regression examined differences by ethnicity in patient characteristics, care pathway and clinical outcomes; multivariable models controlled for potential confounders. Whites (n = 630) and non-Whites (n = 510) differed by age, socioeconomic status, pandemic wave of admission, pregnancy, recorded obesity, previous and current smoking, and presence of chronic obstructive pulmonary disease. After adjustment for a priori confounders non-Whites were less likely to have received pre-admission antibiotics [adjusted odds ratio (aOR) 0·43, 95% confidence interval (CI) 0·28–0·68, P < 0·001) but more likely to receive antiviral drugs as in-patients (aOR 1·53, 95% CI 1·08–2·18, P = 0·018). However, there were no significant differences by ethnicity in delayed admission, severity at presentation for admission, or likelihood of severe outcome. Cambridge University Press 2014-08-01 Article PeerReviewed Nyland, G.A., McKenzie, B.C., Myles, Puja R., Semple, M.G., Lim, W.S., Openshaw, Peter J.M., Read, R.C., Taylor, B.L., Brett, S.J., Mcmenamin, J., Enstone, J.E., Bannister, B., Nicholson, K.G. and Nguyen-Van-Tam, Jonathan (2014) Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK. Epidemiology & Infection, 143 (6). pp. 1129-1138. ISSN 1469-4409 Epidemiology influenza influenza A pandemic https://www.cambridge.org/core/journals/epidemiology-and-infection/article/effect-of-ethnicity-on-care-pathway-and-outcomes-in-patients-hospitalized-with-influenza-ah1n1pdm09-in-the-uk/5990C205BD084C25FD3D8AA3FD820F69 doi:10.1017/S0950268814001873 doi:10.1017/S0950268814001873
spellingShingle Epidemiology
influenza
influenza A
pandemic
Nyland, G.A.
McKenzie, B.C.
Myles, Puja R.
Semple, M.G.
Lim, W.S.
Openshaw, Peter J.M.
Read, R.C.
Taylor, B.L.
Brett, S.J.
Mcmenamin, J.
Enstone, J.E.
Bannister, B.
Nicholson, K.G.
Nguyen-Van-Tam, Jonathan
Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK
title Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK
title_full Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK
title_fullStr Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK
title_full_unstemmed Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK
title_short Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK
title_sort effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza a(h1n1)pdm09 in the uk
topic Epidemiology
influenza
influenza A
pandemic
url https://eprints.nottingham.ac.uk/37740/
https://eprints.nottingham.ac.uk/37740/
https://eprints.nottingham.ac.uk/37740/