Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India

Introduction We are undertaking a randomised controlled trial (fAmily led rehabiliTaTion aftEr stroke in INDia, ATTEND) evaluating training a family carer to enable maximal rehabilitation of patients with stroke-related disability; as a potentially affordable, culturally acceptable and effective int...

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Main Authors: Liu, Hueiming, Lindley, Richard, Alim, Mohammed, Felix, Cynthia, Gandhi, Dorcas B.C., Verma, Schweta J., Tugnawat, Deepak Kumar, Syrigapu, Anuradha, Ramamurthy, Ramaprabhu Krishnappa, Pandian, Jeyaraj D., Walker, Marion F., Forster, Anne, Anderson, Craig S., Langhorne, Peter, Murthy, Gudlavalleti Venkata Satyanarayana, Shamanna, Bindiganavale Ramaswamy, Hackett, Maree L., Maulik, Pallab K, Harvey, Lisa A., Jan, Stephen
Format: Article
Published: BMJ Publishing Group 2016
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Online Access:https://eprints.nottingham.ac.uk/37739/
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author Liu, Hueiming
Lindley, Richard
Alim, Mohammed
Felix, Cynthia
Gandhi, Dorcas B.C.
Verma, Schweta J.
Tugnawat, Deepak Kumar
Syrigapu, Anuradha
Ramamurthy, Ramaprabhu Krishnappa
Pandian, Jeyaraj D.
Walker, Marion F.
Forster, Anne
Anderson, Craig S.
Langhorne, Peter
Murthy, Gudlavalleti Venkata Satyanarayana
Shamanna, Bindiganavale Ramaswamy
Hackett, Maree L.
Maulik, Pallab K,
Harvey, Lisa A.
Jan, Stephen
author_facet Liu, Hueiming
Lindley, Richard
Alim, Mohammed
Felix, Cynthia
Gandhi, Dorcas B.C.
Verma, Schweta J.
Tugnawat, Deepak Kumar
Syrigapu, Anuradha
Ramamurthy, Ramaprabhu Krishnappa
Pandian, Jeyaraj D.
Walker, Marion F.
Forster, Anne
Anderson, Craig S.
Langhorne, Peter
Murthy, Gudlavalleti Venkata Satyanarayana
Shamanna, Bindiganavale Ramaswamy
Hackett, Maree L.
Maulik, Pallab K,
Harvey, Lisa A.
Jan, Stephen
author_sort Liu, Hueiming
building Nottingham Research Data Repository
collection Online Access
description Introduction We are undertaking a randomised controlled trial (fAmily led rehabiliTaTion aftEr stroke in INDia, ATTEND) evaluating training a family carer to enable maximal rehabilitation of patients with stroke-related disability; as a potentially affordable, culturally acceptable and effective intervention for use in India. A process evaluation is needed to understand how and why this complex intervention may be effective, and to capture important barriers and facilitators to its implementation. We describe the protocol for our process evaluation to encourage the development of in-process evaluation methodology and transparency in reporting. Methods and analysis The realist and RE-AIM (Reach, Effectiveness, Adoption, Implementation and Maintenance) frameworks informed the design. Mixed methods include semistructured interviews with health providers, patients and their carers, analysis of quantitative process data describing fidelity and dose of intervention, observations of trial set up and implementation, and the analysis of the cost data from the patients and their families perspective and programme budgets. These qualitative and quantitative data will be analysed iteratively prior to knowing the quantitative outcomes of the trial, and then triangulated with the results from the primary outcome evaluation. Ethics and dissemination The process evaluation has received ethical approval for all sites in India. In low-income and middle-income countries, the available human capital can form an approach to reducing the evidence practice gap, compared with the high cost alternatives available in established market economies. This process evaluation will provide insights into how such a programme can be implemented in practice and brought to scale. Through local stakeholder engagement and dissemination of findings globally we hope to build on patient-centred, cost-effective and sustainable models of stroke rehabilitation. Trial registration number CTRI/2013/04/003557.
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spelling nottingham-377392020-05-04T18:12:16Z https://eprints.nottingham.ac.uk/37739/ Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India Liu, Hueiming Lindley, Richard Alim, Mohammed Felix, Cynthia Gandhi, Dorcas B.C. Verma, Schweta J. Tugnawat, Deepak Kumar Syrigapu, Anuradha Ramamurthy, Ramaprabhu Krishnappa Pandian, Jeyaraj D. Walker, Marion F. Forster, Anne Anderson, Craig S. Langhorne, Peter Murthy, Gudlavalleti Venkata Satyanarayana Shamanna, Bindiganavale Ramaswamy Hackett, Maree L. Maulik, Pallab K, Harvey, Lisa A. Jan, Stephen Introduction We are undertaking a randomised controlled trial (fAmily led rehabiliTaTion aftEr stroke in INDia, ATTEND) evaluating training a family carer to enable maximal rehabilitation of patients with stroke-related disability; as a potentially affordable, culturally acceptable and effective intervention for use in India. A process evaluation is needed to understand how and why this complex intervention may be effective, and to capture important barriers and facilitators to its implementation. We describe the protocol for our process evaluation to encourage the development of in-process evaluation methodology and transparency in reporting. Methods and analysis The realist and RE-AIM (Reach, Effectiveness, Adoption, Implementation and Maintenance) frameworks informed the design. Mixed methods include semistructured interviews with health providers, patients and their carers, analysis of quantitative process data describing fidelity and dose of intervention, observations of trial set up and implementation, and the analysis of the cost data from the patients and their families perspective and programme budgets. These qualitative and quantitative data will be analysed iteratively prior to knowing the quantitative outcomes of the trial, and then triangulated with the results from the primary outcome evaluation. Ethics and dissemination The process evaluation has received ethical approval for all sites in India. In low-income and middle-income countries, the available human capital can form an approach to reducing the evidence practice gap, compared with the high cost alternatives available in established market economies. This process evaluation will provide insights into how such a programme can be implemented in practice and brought to scale. Through local stakeholder engagement and dissemination of findings globally we hope to build on patient-centred, cost-effective and sustainable models of stroke rehabilitation. Trial registration number CTRI/2013/04/003557. BMJ Publishing Group 2016-09-15 Article PeerReviewed Liu, Hueiming, Lindley, Richard, Alim, Mohammed, Felix, Cynthia, Gandhi, Dorcas B.C., Verma, Schweta J., Tugnawat, Deepak Kumar, Syrigapu, Anuradha, Ramamurthy, Ramaprabhu Krishnappa, Pandian, Jeyaraj D., Walker, Marion F., Forster, Anne, Anderson, Craig S., Langhorne, Peter, Murthy, Gudlavalleti Venkata Satyanarayana, Shamanna, Bindiganavale Ramaswamy, Hackett, Maree L., Maulik, Pallab K,, Harvey, Lisa A. and Jan, Stephen (2016) Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India. BMJ, 6 (e01202). pp. 1-8. ISSN 1756-1833 Stroke randomized controlled trial protocol India http://bmjopen.bmj.com/content/6/9/e012027 doi:10.1136/bmjopen-2016-012027 doi:10.1136/bmjopen-2016-012027
spellingShingle Stroke
randomized controlled trial
protocol
India
Liu, Hueiming
Lindley, Richard
Alim, Mohammed
Felix, Cynthia
Gandhi, Dorcas B.C.
Verma, Schweta J.
Tugnawat, Deepak Kumar
Syrigapu, Anuradha
Ramamurthy, Ramaprabhu Krishnappa
Pandian, Jeyaraj D.
Walker, Marion F.
Forster, Anne
Anderson, Craig S.
Langhorne, Peter
Murthy, Gudlavalleti Venkata Satyanarayana
Shamanna, Bindiganavale Ramaswamy
Hackett, Maree L.
Maulik, Pallab K,
Harvey, Lisa A.
Jan, Stephen
Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India
title Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India
title_full Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India
title_fullStr Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India
title_full_unstemmed Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India
title_short Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India
title_sort protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (attend) in india
topic Stroke
randomized controlled trial
protocol
India
url https://eprints.nottingham.ac.uk/37739/
https://eprints.nottingham.ac.uk/37739/
https://eprints.nottingham.ac.uk/37739/