SPAG5 as a prognostic biomarker and chemotherapy sensitivity predictor in breast cancer: a retrospective, integrated genomic, transcriptomic, and protein analysis

QR Code

SPAG5 as a prognostic biomarker and chemotherapy sensitivity predictor in breast cancer: a retrospective, integrated genomic, transcriptomic, and protein analysis

Background Proliferation markers and profiles have been recommended for guiding the choice of systemic treatments for breast cancer. However, the best molecular marker or test to use has not yet been identified. We did this study to identify factors that drive proliferation and its associated fea...

Full description

Bibliographic Details
Main Authors:	Abdel-Fatah, Tarek M.A., Agarwal, Devika, Liu, Dong-Xu, Russell, Roslin, Rueda, Oscar M., Liu, Karen, Xu, Bing, Moseley, Paul M., Green, Andrew R., Pockley, Alan G., Rees, Robert C., Caldas, Carlos, Ellis, Ian O., Ball, Graham R., Chan, Stephen Y.T.
Format:	Article
Published:	Elsevier 2016
Online Access:	https://eprints.nottingham.ac.uk/37734/

Similar Items

Prognostic biomarkers for chemotherapy response on hpe in osteosarcoma patients
by: Ahmed, Farahat Nadeem
Published: (2021)

Human topoisomerase II alpha as a prognostic biomarker in cancer chemotherapy
by: Ali, Yousaf, et al.
Published: (2016)

Transcriptomic and protein expression analysis reveals clinicopathological significance of bloom syndrome helicase (BLM) in breast cancer
by: Arora, Arvind, et al.
Published: (2015)

Association of single nucleotide polymorphisms of SPAG11 gene with semen quality and testicular traits of boer goats
by: Harighi, Mohammadfazel
Published: (2019)

The prognostic and predictive power of redox rotein expression for anthracycline-based chemotherapy response in locally advanced breast cancer
by: Woolston, Caroline M., et al.
Published: (2012)

Integrative analysis of copy number and gene expression in breast cancer using formalin-fixed paraffin-embedded core biopsy tissue: a feasibility study
by: Iddawela, Mahesh, et al.
Published: (2017)

Weight changes during chemotherapy and prognostic outcome in breast cancer: A preliminary assessment in single centre cohort
by: Lua, Pei Lin, et al.
Published: (2016)

Novel SNPs in the SPAG11 gene and association with testicular biometric variables in Boer goats and application of the levelled-container technique
by: Harigh, Mohammad Fazel, et al.
Published: (2019)

Prognostic indicators for naïve canine non-indolent T-cell lymphoma treated with combination lomustine, vincristine, procarbazine and prednisolone chemotherapy
by: Blaxill, J., et al.
Published: (2021)

Prognostic significance of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase protein expression in colorectal cancer patients treated with or without 5-fluorouracil-based chemotherapy
by: Soong, R., et al.
Published: (2008)

Calpain-2 expression is associated with response to platinum based chemotherapy, progression-free and overall survival in ovarian cancer
by: Storr, Sarah J., et al.
Published: (2012)

Persistent pain after wrist or hand fracture: Development and validation of a prognostic model
by: Harrington, Flavia, et al.
Published: (2019)

Nottingham clinico-pathological response index (NPRI) after neoadjuvant chemotherapy (Neo-ACT) accurately predicts clinical outcome in locally advanced breast cancer
by: Abdel-Fatah, T., et al.
Published: (2015)

Prognostic Significance of Cardiac Magnetic Resonance in Left Atrial and Biventricular Strain Analysis during the Follow-Up of Suspected Myocarditis
by: Chen, Y., et al.
Published: (2023)

Impact Of Traditional Prognostic Factor And Chemotherapy Schedule Modification On Breast Cancer Patients: A 5 Year Retrospective Study In A District Specialist Hospital In The State Of Perak
by: Gunasekaran, Gobi Hariyanayagam
Published: (2021)

Applications of calixarenes in cancer chemotherapy: facts and perspectives
by: Ali, Yousaf, et al.
Published: (2015)

PEGylation of paclitaxel for inhaled chemotherapy
by: Luo, Tian
Published: (2016)

Prognostic Value of Cardiac Magnetic Resonance in Assessing Right Ventricular Strain in Cardiovascular Disease: A Systematic Review and Meta-Analysis
by: Bo, K., et al.
Published: (2022)

Molecular responses during chemotherapy in acute myeloid leukemias in predicting poor-response to standard chemotherapy.
by: Abdullah, Maha, et al.
Published: (2009)

RECQL4 helicase has oncogenic potential in sporadic breast cancers
by: Arora, Arvind, et al.
Published: (2016)

The Reciprocal Interaction: Chemotherapy and Tumor Microenvironment
by: Kim, S., et al.
Published: (2011)

The impact on sexual functioning of chemotherapy-induced menopause in women with breast cancer.
by: Rogers, M., et al.
Published: (2002)

Saccharomyces cerevisiae-like 1 (SEC14L1) is a prognostic factor in breast cancer associated with lymphovascular invasion
by: Sonbul, Sultan N., et al.
Published: (2018)

Curcumin combination chemotherapy: the implication and efficacy in cancer
by: Tan, Bee Ling, et al.
Published: (2019)

Managing patients on chemotherapy: a guide for pharmacists
by: Periasamy, Ummavathy, et al.
Published: (2015)

Intraperitoneal chemotherapy following refractory intravenous route in advanced ovarian cancer.
by: Shafiee MN,, et al.
Published: (2013)

Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer
by: Green, Andrew R., et al.
Published: (2016)

Targeting ataxia telangiectasia mutated and Rad3 related kinase (ATR) in PTEN deficient breast cancers for personalized therapy
by: Al-Subhi, Nouf, et al.
Published: (2018)

Prognostic factors for malignant pleural mesothelioma
by: Brims, Fraser, et al.
Published: (2013)

Determination Of Prognostic Markers For Cervical Cancer
by: Ahmad, Rahmatul Wahida
Published: (2008)

Cancer chemotherapy in early life significantly alters the maturation of pain processing
by: Hathway, Gareth J., et al.
Published: (2017)

Nottingham Prognostic Index Plus (NPI+): a modern clinical decision making tool in breast cancer
by: Rakha, Emad, et al.
Published: (2014)

Cost of cancer care for patients undergoing chemotherapy: The Elements of Cancer Care study
by: Ward, R., et al.
Published: (2015)

Impact of chemotherapy on hippocampal neurogenesis and potential protective strategies
by: Lasio, Valeria
Published: (2017)

‘Emergency chemotherapy’ for bleeding cervical cancer: case series
by: Shafiee, MN, et al.
Published: (2012)

Vomiting in docetaxel chemotherapy: which to blame, dose or gene?
by: Jabir, Rafid, et al.
Published: (2014)

Cancer incidence and chemotherapy-induced adverse effects in Asia
by: Khatab, Nasir Ibrahim Omar, et al.
Published: (2019)

The prognostic value of perfusion MRI in cerebral glioma
by: Manita, Muftah
Published: (2012)

An investigation of druggable prognostic markers in paediatric ependymoma
by: Sabnis, Durgagauri
Published: (2016)

Prognostic Markers Of Resistance And Relapse In Acute Leukaemia
by: Pon, Maha Abdullah@Maha-Lakswmi
Published: (2003)