The future of multiple sclerosis treatments

Introduction. There are not many conditions in which the last few decades have brought such a major change in the landscape of treatments as is the case of multiple sclerosis (MS). A number of disease modifying treatments (DMTs) are presently available for the treatment of the inflammatory phase of...

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Main Authors: Coclitu, Catalina, Constantinescu, Cris S., Tanasescu, Radu
Format: Article
Published: Expert Reviews 2016
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Online Access:https://eprints.nottingham.ac.uk/37718/
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author Coclitu, Catalina
Constantinescu, Cris S.
Tanasescu, Radu
author_facet Coclitu, Catalina
Constantinescu, Cris S.
Tanasescu, Radu
author_sort Coclitu, Catalina
building Nottingham Research Data Repository
collection Online Access
description Introduction. There are not many conditions in which the last few decades have brought such a major change in the landscape of treatments as is the case of multiple sclerosis (MS). A number of disease modifying treatments (DMTs) are presently available for the treatment of the inflammatory phase of this disabling disease; however, the need for treating neurodegeneration and halting the progression of disability is still unmet. Areas covered: In this paper we review the available information on existing and emerging DMTs and we discuss their place within the context of different treatment strategies in MS. Expert Commentary: The future of MS treatments should include the development of new treatment strategies tackling disease progression, together with a better understanding of the side-effects and the best sequential strategy of implementation of available and emerging drugs.
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spelling nottingham-377182020-05-04T18:16:05Z https://eprints.nottingham.ac.uk/37718/ The future of multiple sclerosis treatments Coclitu, Catalina Constantinescu, Cris S. Tanasescu, Radu Introduction. There are not many conditions in which the last few decades have brought such a major change in the landscape of treatments as is the case of multiple sclerosis (MS). A number of disease modifying treatments (DMTs) are presently available for the treatment of the inflammatory phase of this disabling disease; however, the need for treating neurodegeneration and halting the progression of disability is still unmet. Areas covered: In this paper we review the available information on existing and emerging DMTs and we discuss their place within the context of different treatment strategies in MS. Expert Commentary: The future of MS treatments should include the development of new treatment strategies tackling disease progression, together with a better understanding of the side-effects and the best sequential strategy of implementation of available and emerging drugs. Expert Reviews 2016-10-21 Article PeerReviewed Coclitu, Catalina, Constantinescu, Cris S. and Tanasescu, Radu (2016) The future of multiple sclerosis treatments. Expert Review of Neurotherapeutics, 16 (12). ISSN 1744-8360 Multiple sclerosis Immunomodulation Monoclonal antibodies Remyelination Repurposing http://www.tandfonline.com/doi/abs/10.1080/14737175.2016.1243056?journalCode=iern20 doi:10.1080/14737175.2016.1243056 doi:10.1080/14737175.2016.1243056
spellingShingle Multiple sclerosis
Immunomodulation
Monoclonal antibodies
Remyelination
Repurposing
Coclitu, Catalina
Constantinescu, Cris S.
Tanasescu, Radu
The future of multiple sclerosis treatments
title The future of multiple sclerosis treatments
title_full The future of multiple sclerosis treatments
title_fullStr The future of multiple sclerosis treatments
title_full_unstemmed The future of multiple sclerosis treatments
title_short The future of multiple sclerosis treatments
title_sort future of multiple sclerosis treatments
topic Multiple sclerosis
Immunomodulation
Monoclonal antibodies
Remyelination
Repurposing
url https://eprints.nottingham.ac.uk/37718/
https://eprints.nottingham.ac.uk/37718/
https://eprints.nottingham.ac.uk/37718/