The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition

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The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition

Kinesins that influence the dynamics of microtubule growth and shrinkage require the ability to distinguish between the microtubule end and the microtubule lattice. The microtubule depolymerizing kinesin MCAK has been shown to specifically recognize the microtubule end. This ability is key to the ac...

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Bibliographic Details
Main Authors:	Patel, Jennifer T., Belsham, Hannah R., Rathbone, Alexandra J., Wickstead, Bill, Gell, Christopher, Friel, Claire T.
Format:	Article
Published:	Royal Society Publishing 2016
Subjects:	MCAK; kinesin-13; microtubule; depolymerization; ATP turnover; microtubule end recognition
Online Access:	https://eprints.nottingham.ac.uk/37614/

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