Structural basis of Lewis(b) antigen binding by the Helicobacter pylori adhesin BabA

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Structural basis of Lewis(b) antigen binding by the Helicobacter pylori adhesin BabA

Helicobacter pylori is a leading cause of peptic ulceration and gastric cancer worldwide. To achieve colonization of the stomach, this Gram-negative bacterium adheres to Lewis(b) (Le(b)) antigens in the gastric mucosa using its outer membrane protein BabA. Structural information for BabA has been el...

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Bibliographic Details
Main Authors:	Hage, Naim, Howard, Tina, Phillips, Chris, Brassington, Claire, Overman, Ross, Debreczeni, Judit, Gellert, Paul, Stolnik, Snow, Winkler, G. Sebastiaan, Falcone, Franco H.
Format:	Article
Published:	American Association for the Advancement of Science 2015
Subjects:	Helicobacter pylori; Adhesin; BabA
Online Access:	https://eprints.nottingham.ac.uk/37535/

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