What's a SNP between friends: the influence of single nucleotide polymorphisms on virulence and phenotypes of Clostridium difficile strain 630 and derivatives

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What's a SNP between friends: the influence of single nucleotide polymorphisms on virulence and phenotypes of Clostridium difficile strain 630 and derivatives

Clostridium difficile is a major cause of antibiotic induced diarrhoea worldwide, responsible for significant annual mortalities and represents a considerable economic burden on healthcare systems. The two main C. difficile virulence factors are toxins A and B. Isogenic toxin B mutants of two indepe...

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Bibliographic Details
Main Authors:	Collery, Mark M., Kuehne, Sarah A., McBride, Shonna M., Kelly, Michelle L., Monot, Marc, Cockayne, Alan, Dupuy, Bruno, Minton, Nigel P.
Format:	Article
Published:	Taylor & Francis 2016
Subjects:	single nucleotide polymorphism; sporulation; motility; toxin expression; mutation; ClosTron; virulence
Online Access:	https://eprints.nottingham.ac.uk/37446/

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