Investigating the genetics of sporadic early-onset Alzheimer’s disease using a customised genotyping chip

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Investigating the genetics of sporadic early-onset Alzheimer’s disease using a customised genotyping chip

Alzheimer’s disease (AD) is the commonest form of dementia and is characterised with neuropathological hallmarks such as aggregated amyloid plaques and hyper-phosphorylated tau protein. One type of AD is autosomal dominant AD (ADAD) which is caused by highly penetrant variants in one of three genes...

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Bibliographic Details
Main Author:	Barber, Imelda Stacey
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Subjects:	Alzheimer's disease Genetic aetiology Neurodegenerative markers Genetic markers
Online Access:	https://eprints.nottingham.ac.uk/37409/

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