Learning lessons from adverse drug reactions in children

Drug toxicity is, unfortunately, a significant problem in children both in the hospital and in the community. Drug toxicity in children is different to that seen in adults. At least one in 500 children will experience an adverse drug reaction each year. For children in hospital, the risk is far grea...

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Main Authors: Sammons, Helen, Choonara, Imti
Format: Article
Published: MDPI 2016
Subjects:
Online Access:https://eprints.nottingham.ac.uk/37194/
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author Sammons, Helen
Choonara, Imti
author_facet Sammons, Helen
Choonara, Imti
author_sort Sammons, Helen
building Nottingham Research Data Repository
collection Online Access
description Drug toxicity is, unfortunately, a significant problem in children both in the hospital and in the community. Drug toxicity in children is different to that seen in adults. At least one in 500 children will experience an adverse drug reaction each year. For children in hospital, the risk is far greater (one in ten). Additionally, different and sometimes unique adverse drug reactions are seen in the paediatric age groups. Some of the major cases of drug toxicity historically have occurred in neonates. It is important that we understand the mechanism of action of adverse drug reactions. Greater understanding alongside rational prescribing should hopefully reduce drug toxicity in children in the future.
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spelling nottingham-371942020-05-04T17:32:57Z https://eprints.nottingham.ac.uk/37194/ Learning lessons from adverse drug reactions in children Sammons, Helen Choonara, Imti Drug toxicity is, unfortunately, a significant problem in children both in the hospital and in the community. Drug toxicity in children is different to that seen in adults. At least one in 500 children will experience an adverse drug reaction each year. For children in hospital, the risk is far greater (one in ten). Additionally, different and sometimes unique adverse drug reactions are seen in the paediatric age groups. Some of the major cases of drug toxicity historically have occurred in neonates. It is important that we understand the mechanism of action of adverse drug reactions. Greater understanding alongside rational prescribing should hopefully reduce drug toxicity in children in the future. MDPI 2016-01-08 Article PeerReviewed Sammons, Helen and Choonara, Imti (2016) Learning lessons from adverse drug reactions in children. Children, 3 (1). ISSN 2227-9067 drug toxicity; children; drug metabolism; rational drug use http://www.mdpi.com/2227-9067/3/1/1 doi:10.3390/children3010001 doi:10.3390/children3010001
spellingShingle drug toxicity; children; drug metabolism; rational drug use
Sammons, Helen
Choonara, Imti
Learning lessons from adverse drug reactions in children
title Learning lessons from adverse drug reactions in children
title_full Learning lessons from adverse drug reactions in children
title_fullStr Learning lessons from adverse drug reactions in children
title_full_unstemmed Learning lessons from adverse drug reactions in children
title_short Learning lessons from adverse drug reactions in children
title_sort learning lessons from adverse drug reactions in children
topic drug toxicity; children; drug metabolism; rational drug use
url https://eprints.nottingham.ac.uk/37194/
https://eprints.nottingham.ac.uk/37194/
https://eprints.nottingham.ac.uk/37194/