STAT5 induces miR-21 expression in cutaneous T cell lymphoma

STAT5 induces miR-21 expression in cutaneous T cell lymphoma

In cutaneous T cell lymphomas (CTCL), miR-21 is aberrantly expressed in skin and peripheral blood and displays anti-apoptotic properties in malignant T cells. It is, however, unclear exactly which cells express miR-21 and what mechanisms regulate miR-21. Here, we demonstrate miR-21 expression in sit...

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Bibliographic Details
Main Authors: Lindahl, Lise M., Fredholm, Simon, Joseph, Claudine, Nielsen, Boye Schnack, Jønson, Lars, Willerslev-Olsen, Andreas, Gluud, Maria, Blümel, Edda, Petersen, David L., Sibbesen, Nina, Hu, Tengpeng, Nastasi, Claudia, Krejsgaard, Thorbjørn, Jæhger, Ditte, Persson, Jenny L., Mongan, Nigel P., Wasik, Mariusz A., Litvinov, Ivan V., Sasseville, Denis, Koralov, Sergei B., Bonefeld, Charlotte M., Geisler, Carsten, Woetmann, Anders, Ralfkiaer, Elisabeth, Iversen, Lars, Odum, Niels
Format: Article
Published: Impact 2016
Subjects:
MiR-21
in situ
STAT5
IL-2
Cutaneous T-cell lymphoma (CTCL)
Online Access:https://eprints.nottingham.ac.uk/36661/

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