Dissecting the mechanism of growth inhibition and tumour reversion mediated by oocyte extract in human breast cancer cells

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Dissecting the mechanism of growth inhibition and tumour reversion mediated by oocyte extract in human breast cancer cells

Axolotl oocyte extract (AOE) has the ability to reprogram the breast cancer cell epigenome by modifying DNA methylation and histone modifications at the promoter region of silenced tumour suppressor genes, resulting in loss of cellular tumourigenicity (Allegrucci et al., 2011). The present study aim...

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Bibliographic Details
Main Author:	Saad, Norazalina
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Online Access:	https://eprints.nottingham.ac.uk/36226/

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