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Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis

Triglycerides (TG) are one of the most common excipients used in oral lipid-based formulations. The chain length of the TG plays an important role in the oral bioavailability of the co-administered drug. Fatty acid (FA) chain-length specificity of porcine pancreatic lipase was studied by means of an...

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Bibliographic Details
Main Authors:	Benito-Gallo, Paloma, Franceschetto, Alessandro, Wong, Jonathan C.M., Marlow, Maria, Zann, Vanessa, Scholes, Peter, Gershkovich, Pavel
Format:	Article
Published:	Elsevier 2015
Subjects:	Lipid based drug delivery systems; Poorly water-soluble drugs; Oral bioavailability; Back-titration; Fatty acid; Monoglyceride
Online Access:	https://eprints.nottingham.ac.uk/36108/

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