Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit)
Background: Text message cessation programmes have potential to change smoking behaviour during pregnancy but their effectiveness is unknown. This study aimed to estimate key parameters, including effectiveness and cost-effectiveness, for delivering a definitive effectiveness trial of a pregnancy sp...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Conference or Workshop Item |
| Published: |
2016
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| Online Access: | https://eprints.nottingham.ac.uk/36030/ |
| _version_ | 1848795208410464256 |
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| author | Naughton, Felix Foster, Katharine Emery, Jo Cooper, Sue Sutton, Stephen Leonardi-Bee, Jo Jones, Matthew Ussher, Michael Whitemore, Rachel Leighton, Matthew Montgomery, Alan Parrott, Steve Coleman, Tim |
| author_facet | Naughton, Felix Foster, Katharine Emery, Jo Cooper, Sue Sutton, Stephen Leonardi-Bee, Jo Jones, Matthew Ussher, Michael Whitemore, Rachel Leighton, Matthew Montgomery, Alan Parrott, Steve Coleman, Tim |
| author_sort | Naughton, Felix |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Background: Text message cessation programmes have potential to change smoking behaviour during pregnancy but their effectiveness is unknown. This study aimed to estimate key parameters, including effectiveness and cost-effectiveness, for delivering a definitive effectiveness trial of a pregnancy specific, theory-guided, tailored text message cessation intervention.
Methods: Multicentre, single-blinded, randomised controlled trial. Pregnant smokers (<25 weeks gestation) were recruited from 16 antenatal screening clinics in England. Control participants received usual care and a smoking cessation leaflet. Intervention participants received the control components plus 12 weeks of individually-tailored, automated, interactive, cessation text messages (MiQuit). Key parameters to inform a full trial were recruitment and outcome ascertainment rates. 7 smoking outcomes were assessed; the planned primary outcome for the full trial was continuous abstinence from 4 weeks post-randomisation until 36 weeks gestation, validated biochemically. Estimated costs were modelled per quitter and per QALY.
Findings: 407 participants (203 MiQuit, 204 control) were randomised, 39% of those eligible. At follow-up, similar proportions per group provided self-report smoking status and a validation sample. More MiQuit participants achieved validated continuous abstinence relative to controls (5.4% vs. 2.0%; odds ratio [adjusted for site and gestation] 2.7, 95% CI 0.93 to 9.35). Adjusted odds ratios on other smoking outcomes ranged from 1.03 to 3.28 in favour of MiQuit. Incremental costs per quitter/QALY were £140.91 (95% CI -£192.87 to £617.96)/£3,623.09 (-£4,926.56 to £16,197.20), respectively, at the end of pregnancy.
Discussion: Findings imply that this low-cost text message intervention is likely to be effective and cost-effective. A full trial is warranted. |
| first_indexed | 2025-11-14T19:28:26Z |
| format | Conference or Workshop Item |
| id | nottingham-36030 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:28:26Z |
| publishDate | 2016 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-360302024-08-15T15:19:43Z https://eprints.nottingham.ac.uk/36030/ Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit) Naughton, Felix Foster, Katharine Emery, Jo Cooper, Sue Sutton, Stephen Leonardi-Bee, Jo Jones, Matthew Ussher, Michael Whitemore, Rachel Leighton, Matthew Montgomery, Alan Parrott, Steve Coleman, Tim Background: Text message cessation programmes have potential to change smoking behaviour during pregnancy but their effectiveness is unknown. This study aimed to estimate key parameters, including effectiveness and cost-effectiveness, for delivering a definitive effectiveness trial of a pregnancy specific, theory-guided, tailored text message cessation intervention. Methods: Multicentre, single-blinded, randomised controlled trial. Pregnant smokers (<25 weeks gestation) were recruited from 16 antenatal screening clinics in England. Control participants received usual care and a smoking cessation leaflet. Intervention participants received the control components plus 12 weeks of individually-tailored, automated, interactive, cessation text messages (MiQuit). Key parameters to inform a full trial were recruitment and outcome ascertainment rates. 7 smoking outcomes were assessed; the planned primary outcome for the full trial was continuous abstinence from 4 weeks post-randomisation until 36 weeks gestation, validated biochemically. Estimated costs were modelled per quitter and per QALY. Findings: 407 participants (203 MiQuit, 204 control) were randomised, 39% of those eligible. At follow-up, similar proportions per group provided self-report smoking status and a validation sample. More MiQuit participants achieved validated continuous abstinence relative to controls (5.4% vs. 2.0%; odds ratio [adjusted for site and gestation] 2.7, 95% CI 0.93 to 9.35). Adjusted odds ratios on other smoking outcomes ranged from 1.03 to 3.28 in favour of MiQuit. Incremental costs per quitter/QALY were £140.91 (95% CI -£192.87 to £617.96)/£3,623.09 (-£4,926.56 to £16,197.20), respectively, at the end of pregnancy. Discussion: Findings imply that this low-cost text message intervention is likely to be effective and cost-effective. A full trial is warranted. 2016-08-25 Conference or Workshop Item PeerReviewed Naughton, Felix, Foster, Katharine, Emery, Jo, Cooper, Sue, Sutton, Stephen, Leonardi-Bee, Jo, Jones, Matthew, Ussher, Michael, Whitemore, Rachel, Leighton, Matthew, Montgomery, Alan, Parrott, Steve and Coleman, Tim (2016) Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit). In: European Health Psychology Society and British Psychological Society Division of Health Psychology Conference 2016 (EHPS/DHP 2016), 23-27 Aug 2016, Aberdeen, UK. |
| spellingShingle | Naughton, Felix Foster, Katharine Emery, Jo Cooper, Sue Sutton, Stephen Leonardi-Bee, Jo Jones, Matthew Ussher, Michael Whitemore, Rachel Leighton, Matthew Montgomery, Alan Parrott, Steve Coleman, Tim Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit) |
| title | Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit) |
| title_full | Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit) |
| title_fullStr | Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit) |
| title_full_unstemmed | Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit) |
| title_short | Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit) |
| title_sort | multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (miquit) |
| url | https://eprints.nottingham.ac.uk/36030/ |