A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children
Background: Systematic reviews and a network meta-analysis show home safety education with or without the provision of safety equipment is effective in promoting poison prevention behaviours in households with children. This paper compares the cost-effectiveness of home safety interventions to promo...
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| Format: | Article |
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BioMed Central
2016
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| Online Access: | https://eprints.nottingham.ac.uk/35990/ |
| _version_ | 1848795204043145216 |
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| author | Achana, Felix Sutton, Alex J. Kendrick, Denise Hayes, Mike Jones, David R. Hubbard, Stephanie J. Cooper, Nicola J. |
| author_facet | Achana, Felix Sutton, Alex J. Kendrick, Denise Hayes, Mike Jones, David R. Hubbard, Stephanie J. Cooper, Nicola J. |
| author_sort | Achana, Felix |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Background: Systematic reviews and a network meta-analysis show home safety education with or without the provision of safety equipment is effective in promoting poison prevention behaviours in households with children. This paper compares the cost-effectiveness of home safety interventions to promote poison prevention practices.
Methods: A probabilistic decision-analytic model simulates healthcare costs and benefits for a hypothetical cohort of under 5 year olds. The model compares the cost-effectiveness of home safety education, home safety inspections, provision of free or low cost safety equipment and fitting of equipment. Analyses are conducted from a UK National Health Service and Personal Social Services perspective and expressed in 2012 prices.
Results: Education without safety inspection, provision or fitting of equipment was the most cost-effective strategy for promoting safe storage of medicines with an incremental cost-effectiveness ratio of £2888 (95 % credible interval (CrI) £1990–£5774) per poison case avoided or £41,330 (95%CrI £20,007–£91,534) per QALY gained compared with usual care. Compared to usual care, home safety interventions were not cost-effective in promoting safe storage of other household products.
Conclusion: Education offers better value for money than more intensive but expensive strategies for preventing medicinal poisonings, but is only likely to be cost-effective at £30,000 per QALY gained for families in disadvantaged areas and for those with more than one child. There was considerable uncertainty in cost-effectiveness estimates due to paucity of evidence on model parameters. Policy makers should consider both costs and effectiveness of competing interventions to ensure efficient use of resources. |
| first_indexed | 2025-11-14T19:28:22Z |
| format | Article |
| id | nottingham-35990 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:28:22Z |
| publishDate | 2016 |
| publisher | BioMed Central |
| recordtype | eprints |
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| spelling | nottingham-359902020-05-04T18:07:50Z https://eprints.nottingham.ac.uk/35990/ A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children Achana, Felix Sutton, Alex J. Kendrick, Denise Hayes, Mike Jones, David R. Hubbard, Stephanie J. Cooper, Nicola J. Background: Systematic reviews and a network meta-analysis show home safety education with or without the provision of safety equipment is effective in promoting poison prevention behaviours in households with children. This paper compares the cost-effectiveness of home safety interventions to promote poison prevention practices. Methods: A probabilistic decision-analytic model simulates healthcare costs and benefits for a hypothetical cohort of under 5 year olds. The model compares the cost-effectiveness of home safety education, home safety inspections, provision of free or low cost safety equipment and fitting of equipment. Analyses are conducted from a UK National Health Service and Personal Social Services perspective and expressed in 2012 prices. Results: Education without safety inspection, provision or fitting of equipment was the most cost-effective strategy for promoting safe storage of medicines with an incremental cost-effectiveness ratio of £2888 (95 % credible interval (CrI) £1990–£5774) per poison case avoided or £41,330 (95%CrI £20,007–£91,534) per QALY gained compared with usual care. Compared to usual care, home safety interventions were not cost-effective in promoting safe storage of other household products. Conclusion: Education offers better value for money than more intensive but expensive strategies for preventing medicinal poisonings, but is only likely to be cost-effective at £30,000 per QALY gained for families in disadvantaged areas and for those with more than one child. There was considerable uncertainty in cost-effectiveness estimates due to paucity of evidence on model parameters. Policy makers should consider both costs and effectiveness of competing interventions to ensure efficient use of resources. BioMed Central 2016-08-03 Article PeerReviewed Achana, Felix, Sutton, Alex J., Kendrick, Denise, Hayes, Mike, Jones, David R., Hubbard, Stephanie J. and Cooper, Nicola J. (2016) A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children. BMC Public Health, 16 . 705/1-705/17. ISSN 1471-2458 Economic evaluation; Public health; Injury prevention; Poisonings; Children; Decision models http://dx.doi.org/10.1186/s12889-016-3334-0 doi:10.1186/s12889-016-3334-0 doi:10.1186/s12889-016-3334-0 |
| spellingShingle | Economic evaluation; Public health; Injury prevention; Poisonings; Children; Decision models Achana, Felix Sutton, Alex J. Kendrick, Denise Hayes, Mike Jones, David R. Hubbard, Stephanie J. Cooper, Nicola J. A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children |
| title | A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children |
| title_full | A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children |
| title_fullStr | A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children |
| title_full_unstemmed | A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children |
| title_short | A decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children |
| title_sort | decision analytic model to investigate the cost-effectiveness of poisoning prevention practices in households with young children |
| topic | Economic evaluation; Public health; Injury prevention; Poisonings; Children; Decision models |
| url | https://eprints.nottingham.ac.uk/35990/ https://eprints.nottingham.ac.uk/35990/ https://eprints.nottingham.ac.uk/35990/ |