cAMP mediated regulation of fibroblast to myofibroblast differentiation in idiopathic pulmonary fibrosis

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cAMP mediated regulation of fibroblast to myofibroblast differentiation in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease with no effective treatment. Myofibroblasts contribute to the pathology of IPF by secreting large amounts of extracellular matrix proteins such as alpha smooth muscle actin (α-SMA) and Collagen I (Col 1). Myofibroblasts have reduced Pros...

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Bibliographic Details
Main Author:	Wright, Rebecca
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Subjects:	Pulmonary fibrosis Myofibroblasts PGE2 cAMP levels
Online Access:	https://eprints.nottingham.ac.uk/35925/

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