Eligibility for and prescription of urate-lowering treatment in patients with incident gout in England

Gout is caused by urate crystal deposition secondary to persistent hyperuricemia. Current guidelines recommend urate-lowering treatment to prevent crystal deposition and encourage crystal dissolution for patients with more severe gout or concomitant conditions.1,2 However, after the first diagnosis,...

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Bibliographic Details
Main Authors: Kuo, Chang-Fu, Grainge, Matthew J., Mallen, Christian, Zhang, Weiya, Doherty, Michael
Format: Article
Published: American Medical Association 2014
Online Access:https://eprints.nottingham.ac.uk/35899/
Description
Summary:Gout is caused by urate crystal deposition secondary to persistent hyperuricemia. Current guidelines recommend urate-lowering treatment to prevent crystal deposition and encourage crystal dissolution for patients with more severe gout or concomitant conditions.1,2 However, after the first diagnosis, it remains unclear when such treatment is appropriate. We investigated the timing of eligibility for and prescription of urate-lowering treatment following first gout diagnosis and factors associated with prescription.