Consequences of late-stage non-small cell lung cancer cachexia on muscle metabolic processes

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Consequences of late-stage non-small cell lung cancer cachexia on muscle metabolic processes

Introduction: Loss of muscle is common in patients with advanced non-small cell lung cancer (NSCLC), and contributes to the high morbidity and mortality of this group. The exact mechanisms behind the loss of muscle are unclear. Patients and methods: To investigate this, 4 patients with stage IV NS...

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Bibliographic Details
Main Authors:	Murton, Andrew J., Maddocks, Matthew, Stephens, Francis B., Marimuthu, Kanagaraj, England, Ruth, Wilcock, Andrew
Format:	Article
Published:	Elsevier 2016
Subjects:	Muscle protein synthesis; proteolysis; cachexia; mTOR signalling; ubiquitin proteasome system
Online Access:	https://eprints.nottingham.ac.uk/35817/

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