In vitro models of medulloblastoma: choosing the right tool for the job

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In vitro models of medulloblastoma: choosing the right tool for the job

The recently-defined four molecular subgroups of medulloblastoma have required updating of our understanding of in vitro models to include molecular classification and risk stratification features from clinical practice. This review seeks to build a more comprehensive picture of the in vitro systems...

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Bibliographic Details
Main Authors:	Ivanov, Delyan P., Coyle, Beth, Walker, David A., Grabowska, Anna M.
Format:	Article
Published:	Elsevier 2016
Subjects:	brain tumor children; cell line molecular subgroups; WNT SHH Group 3 Group 4; three-dimensional cell culture; neurotoxicity testing; normal brain co-culture
Online Access:	https://eprints.nottingham.ac.uk/35789/

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