Synthesis and evaluation of inhibitors of cell wall biosynthesis in Mycobacterium tuberculosis

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Synthesis and evaluation of inhibitors of cell wall biosynthesis in Mycobacterium tuberculosis

The emergence of drug-resistant strains of tuberculosis has led to a demand for the development of new antibiotics. One new target is the cell wall biosynthesis enzyme UDP-Galp mutase (UGM), which aids the formation of the bacteria’s characteristic mycolic acid cell wall. LQ10 and LQ6 were discovere...

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Bibliographic Details
Main Author:	May, Terry J.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Subjects:	drug resistance tuberculosis antibiotics
Online Access:	https://eprints.nottingham.ac.uk/35769/

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