Exploiting the plasticity of primary and secondary response mechanisms in artificial immune systems
One of the key properties of the human immune system is to detect the presence of pathogens, and as such there are numberous immune algorithm which perform anomaly detection and pattern recognition. An additional facet of the human immune system is that an appropriate effector response is generated...
| Main Authors: | , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
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2016
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| Online Access: | https://eprints.nottingham.ac.uk/35766/ |
| _version_ | 1848795156958937088 |
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| author | Greensmith, Julie Jackson, Andrew M. Spendlove, Ian |
| author_facet | Greensmith, Julie Jackson, Andrew M. Spendlove, Ian |
| author_sort | Greensmith, Julie |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | One of the key properties of the human immune system is to detect the presence of pathogens, and as such there are numberous immune algorithm which perform anomaly detection and pattern recognition. An additional facet of the human immune system is that an appropriate effector response is generated upon the detection of a pathogen - a process termed the primary response. Additionally the human immune system has the ability to remember the appropriate response to a particular pathogen - the secondary response. The complex orchestration of both the primary and secondary responses are highly dynamic - described in immunological terms as plastic. In this paper we present an overview of the the exact mechanisms of the generation of a T-helper cell primary response and the mechanisms by which it instructs secondary responses and discuss how this can be computationally useful in artificial immune system development. |
| first_indexed | 2025-11-14T19:27:37Z |
| format | Conference or Workshop Item |
| id | nottingham-35766 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T19:27:37Z |
| publishDate | 2016 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-357662017-10-18T17:48:20Z https://eprints.nottingham.ac.uk/35766/ Exploiting the plasticity of primary and secondary response mechanisms in artificial immune systems Greensmith, Julie Jackson, Andrew M. Spendlove, Ian One of the key properties of the human immune system is to detect the presence of pathogens, and as such there are numberous immune algorithm which perform anomaly detection and pattern recognition. An additional facet of the human immune system is that an appropriate effector response is generated upon the detection of a pathogen - a process termed the primary response. Additionally the human immune system has the ability to remember the appropriate response to a particular pathogen - the secondary response. The complex orchestration of both the primary and secondary responses are highly dynamic - described in immunological terms as plastic. In this paper we present an overview of the the exact mechanisms of the generation of a T-helper cell primary response and the mechanisms by which it instructs secondary responses and discuss how this can be computationally useful in artificial immune system development. 2016-07-20 Conference or Workshop Item PeerReviewed application/pdf en https://eprints.nottingham.ac.uk/35766/1/PlasticPSR_Abstract.pdf Greensmith, Julie, Jackson, Andrew M. and Spendlove, Ian (2016) Exploiting the plasticity of primary and secondary response mechanisms in artificial immune systems. In: Genetic and Evolutionary Computation Conference (2016), 20-24 Jul 2016, Denver, USA. Artificial Immune Systems; Primary and Secondary Response http://dl.acm.org/citation.cfm?doid=2908961.2908962 10.1145/2908961.2908962 10.1145/2908961.2908962 10.1145/2908961.2908962 |
| spellingShingle | Artificial Immune Systems; Primary and Secondary Response Greensmith, Julie Jackson, Andrew M. Spendlove, Ian Exploiting the plasticity of primary and secondary response mechanisms in artificial immune systems |
| title | Exploiting the plasticity of primary and secondary response mechanisms in artificial immune systems |
| title_full | Exploiting the plasticity of primary and secondary response mechanisms in artificial immune systems |
| title_fullStr | Exploiting the plasticity of primary and secondary response mechanisms in artificial immune systems |
| title_full_unstemmed | Exploiting the plasticity of primary and secondary response mechanisms in artificial immune systems |
| title_short | Exploiting the plasticity of primary and secondary response mechanisms in artificial immune systems |
| title_sort | exploiting the plasticity of primary and secondary response mechanisms in artificial immune systems |
| topic | Artificial Immune Systems; Primary and Secondary Response |
| url | https://eprints.nottingham.ac.uk/35766/ https://eprints.nottingham.ac.uk/35766/ https://eprints.nottingham.ac.uk/35766/ |