STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling

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STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling

STAT1 is an indispensable component of a heterotrimer (ISGF3) and a STAT1 homodimer (GAF) that function as transcription regulators in type 1 and type 2 interferon signaling, respectively. To investigate the importance of STAT1-cooperative DNA binding, we generated gene-targeted mice expressing coop...

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Bibliographic Details
Main Authors:	Begitt, Andreas, Droescher, Mathias, Meyer, Thomas, Schmid, Christoph D., Baker, Michelle, Antunes, Filipa, Owen, Markus R., Naumann, Ronald, Decker, Thomas, Vinkemeier, Uwe
Format:	Article
Published:	Nature Publishing Group 2014
Online Access:	https://eprints.nottingham.ac.uk/35709/

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