A role for the sodium pump in H2O2-induced vasorelaxation in porcine isolated coronary arteries

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A role for the sodium pump in H2O2-induced vasorelaxation in porcine isolated coronary arteries

Hydrogen peroxide (H2O2) has been proposed to act as a factor for endothelium-derived hyperpolar-ization (EDH) and EDH may act as a ‘back up’ system to compensate the loss of the NO pathway. Here,the mechanism of action of H2O2in porcine isolated coronary arteries (PCAs) was investigated. DistalPCAs...

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Bibliographic Details
Main Authors:	Wong, P.S., Garle, M.J., Alexander, S.P.H., Randall, M.D., Roberts, R.E.
Format:	Article
Published:	Elsevier 2014
Subjects:	Hydrogen peroxide (H2O2) relaxation; Ouabain-sensitive sodium–potassium pump; KCl relaxation; Rubidium uptake; Ca2+-reintroduction; Porcine coronary artery
Online Access:	https://eprints.nottingham.ac.uk/35683/

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