Hyperoxic gassing with Tiron enhances bradykinin-induced endothelium-dependent and EDH-type relaxation through generation of hydrogen peroxide

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Hyperoxic gassing with Tiron enhances bradykinin-induced endothelium-dependent and EDH-type relaxation through generation of hydrogen peroxide

Oxygenation with 95%O2is routinely used in organ bath studies. However, hyperoxia may affect tissueresponses, particularly in studies which involve reactive oxygen species (ROS). Here, the effects of theantioxidant, Tiron, were investigated under different gassing conditions in the porcine isolated...

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Bibliographic Details
Main Authors:	Wong, Pui San, Roberts, Richard E., Randall, Michael D.
Format:	Article
Published:	Elsevier 2015
Subjects:	Tiron; Bradykinin; Amplex Red; Porcine coronary arteries (PCAs); Hydrogen peroxide (H2O2); Gassing conditions
Online Access:	https://eprints.nottingham.ac.uk/35679/

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