Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India

Objective: The study objective was to compare haemoglobin measurements between the NBM 200 (non-invasive haemoglobin sensor) and Sahli’s hemometer in adolescent girls in a rural Indian setting. Methods: Participants included girls aged between 13 to 17 years from 34 villages in Tuljapur and Lohar...

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Main Authors: Ahankari, Anand S., Dixit, J.V., Fogarty, Andrew W., Tata, Laila J., Myles, Puja R.
Format: Article
Published: BMJ 2016
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Online Access:https://eprints.nottingham.ac.uk/35528/
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author Ahankari, Anand S.
Dixit, J.V.
Fogarty, Andrew W.
Tata, Laila J.
Myles, Puja R.
author_facet Ahankari, Anand S.
Dixit, J.V.
Fogarty, Andrew W.
Tata, Laila J.
Myles, Puja R.
author_sort Ahankari, Anand S.
building Nottingham Research Data Repository
collection Online Access
description Objective: The study objective was to compare haemoglobin measurements between the NBM 200 (non-invasive haemoglobin sensor) and Sahli’s hemometer in adolescent girls in a rural Indian setting. Methods: Participants included girls aged between 13 to 17 years from 34 villages in Tuljapur and Lohara blocks of Osmanabad district, Maharashtra, India. Haemoglobin (Hb) measurements from the non-invasive sensor (NBM 200) were compared with measurements obtained from Sahli’s hemometer using Bland-Altman plot, Spearman correlation coefficient, sensitivity, specificity, and area under the receiver operating characteristic curve analysis (AUROC). Results: Paired measurements from both methods were obtained from 766 adolescent girls (N=766). Haemoglobin levels estimated by Sahli’s hemometer ranged from 5.0 g/dL to 14.0 g/dL (mean: 10.1 g/dL, standard deviation (SD): 1.41), whereas measurements obtained from the NBM 200 ranged from 9.5 g/dL to 15.2 g/dL (mean: 12.8 g/dL, SD: 1.42). The Bland-Altman analysis indicated a mean difference of -2.70 g/dL (95% Confidence Intervals: -2.84 to -2.55) demonstrating an overestimation of Hb measurement by the NBM 200 compared to the Sahli’s hemometer measurements. The NBM 200 showed low sensitivity (23.6%) and moderate specificity (61.8%) for the diagnosis of anaemia. The AUROC score was 0.43 indicating an underestimation of anaemia in our study population by the NBM 200. Conclusion: Haemoglobin measurements obtained from the NBM 200 were consistently higher leading to an underestimation of anaemia prevalence compared with Sahli’s hemometer estimates among adolescent girls in India.
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spelling nottingham-355282020-05-04T18:08:13Z https://eprints.nottingham.ac.uk/35528/ Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India Ahankari, Anand S. Dixit, J.V. Fogarty, Andrew W. Tata, Laila J. Myles, Puja R. Objective: The study objective was to compare haemoglobin measurements between the NBM 200 (non-invasive haemoglobin sensor) and Sahli’s hemometer in adolescent girls in a rural Indian setting. Methods: Participants included girls aged between 13 to 17 years from 34 villages in Tuljapur and Lohara blocks of Osmanabad district, Maharashtra, India. Haemoglobin (Hb) measurements from the non-invasive sensor (NBM 200) were compared with measurements obtained from Sahli’s hemometer using Bland-Altman plot, Spearman correlation coefficient, sensitivity, specificity, and area under the receiver operating characteristic curve analysis (AUROC). Results: Paired measurements from both methods were obtained from 766 adolescent girls (N=766). Haemoglobin levels estimated by Sahli’s hemometer ranged from 5.0 g/dL to 14.0 g/dL (mean: 10.1 g/dL, standard deviation (SD): 1.41), whereas measurements obtained from the NBM 200 ranged from 9.5 g/dL to 15.2 g/dL (mean: 12.8 g/dL, SD: 1.42). The Bland-Altman analysis indicated a mean difference of -2.70 g/dL (95% Confidence Intervals: -2.84 to -2.55) demonstrating an overestimation of Hb measurement by the NBM 200 compared to the Sahli’s hemometer measurements. The NBM 200 showed low sensitivity (23.6%) and moderate specificity (61.8%) for the diagnosis of anaemia. The AUROC score was 0.43 indicating an underestimation of anaemia in our study population by the NBM 200. Conclusion: Haemoglobin measurements obtained from the NBM 200 were consistently higher leading to an underestimation of anaemia prevalence compared with Sahli’s hemometer estimates among adolescent girls in India. BMJ 2016-10-01 Article PeerReviewed Ahankari, Anand S., Dixit, J.V., Fogarty, Andrew W., Tata, Laila J. and Myles, Puja R. (2016) Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India. BMJ Innovations, 2 . pp. 144-148. ISSN 2055-642X Adolescent Sahli’s hemometer Anaemia Non-invasive Haemoglobin NBM 200 India http://innovations.bmj.com/content/2/4/144 doi:10.1136/bmjinnov-2016-000139 doi:10.1136/bmjinnov-2016-000139
spellingShingle Adolescent
Sahli’s hemometer
Anaemia
Non-invasive Haemoglobin
NBM 200
India
Ahankari, Anand S.
Dixit, J.V.
Fogarty, Andrew W.
Tata, Laila J.
Myles, Puja R.
Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India
title Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India
title_full Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India
title_fullStr Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India
title_full_unstemmed Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India
title_short Comparison of the NBM 200 non-invasive haemoglobin sensor with Sahli’s hemometer among adolescent girls in rural India
title_sort comparison of the nbm 200 non-invasive haemoglobin sensor with sahli’s hemometer among adolescent girls in rural india
topic Adolescent
Sahli’s hemometer
Anaemia
Non-invasive Haemoglobin
NBM 200
India
url https://eprints.nottingham.ac.uk/35528/
https://eprints.nottingham.ac.uk/35528/
https://eprints.nottingham.ac.uk/35528/