Genes associated with polymorphic variants predicting lung function are differentially expressed during human lung development

QR Code

Genes associated with polymorphic variants predicting lung function are differentially expressed during human lung development

Background Recent meta-analyses of genome-wide association studies have identified single nucleotide polymorphisms (SNPs) within/near 54 genes associated with lung function measures. Current understanding of the contribution of these genes to human lung development is limited. We set out to furthe...

Full description

Bibliographic Details
Main Authors:	Miller, Suzanne, Melén, Erik, Merid, S. K., Hall, Ian P., Sayers, Ian
Format:	Article
Published:	BioMed Central 2016
Subjects:	Lung function; development; expression; genetics; TMEM163; CDC123
Online Access:	https://eprints.nottingham.ac.uk/35521/

Similar Items

Functional genetics of lung function associated gene GPR126
by: Hall, Robert
Published: (2020)

Translating lung function genome-wide association study (GWAS) findings: new insights for lung biology
by: Kheirallah, Alexander K., et al.
Published: (2016)

The acute impact of a hematopoietic allograft on lung function and inflammation: a prospective observational study
by: Enocson, Alexandra, et al.
Published: (2013)

An in vivo genetic screen of lung function candidate genes using tissue-specific RNAi in Drosophila melanogaster
by: Szamek, Emma
Published: (2025)

Household air pollution and lung function in Indian adults: a cross-sectional study
by: Dave, Mona, et al.
Published: (2017)

Age at menarche and lung function: a Mendelian randomization study
by: Gill, Dipender, et al.
Published: (2017)

Identification of candidate genes expressions and polymorphisms associated with atherosclerosis from postmortem cases in Hospital Kuala Lumpur and Hospital Serdang, Malaysia
by: Blin, Joan
Published: (2013)

Surgical lung biopsy for the diagnosis of interstitial lung disease in England: 1997-2008
by: Hutchinson, John P., et al.
Published: (2016)

Lung mechanics and hyperpolarised gas MRI
by: Thorpe, James
Published: (2018)

Factors influencing the diagnosis and subsequent prognosis in patients with lung cancer
by: O'Dowd, Emma Louise
Published: (2017)

Nephronectin and the genetics of lung function variability
by: Qian, Guoqing
Published: (2023)

Route of exposure alters inflammation and lung function responses to diesel exhaust
by: Larcombe, A., et al.
Published: (2014)

Identification of differentially regulated genes in breast (MCF-7) and lung (H1299) cancer cell lines during Newcastle disease virus strain AF2240 infection
by: Roslan, Nurhidayah
Published: (2012)

Measures of body habitus are associated with lung function in adults with cystic fibrosis: a population-based study
by: Forrester, Doug L., et al.
Published: (2013)

In-hospital mortality following surgical lung biopsy for interstitial lung disease in the USA: 2000-2011
by: Hutchinson, John P., et al.
Published: (2016)

Which patients are assessed by lung cancer nurse specialists? A national lung cancer audit study of over 128,000 patients across England
by: Khakwani, Aamir, et al.
Published: (2016)

Effects of Dietary Beta-Carotene on Lung Function, Respiratory Symptoms and Chronic Obstructive Pulmonary Disease
by: Lee, Andy
Published: (2013)

Exercise training for people following lung resection for non-small cell lung cancer - A Cochrane systematic review
by: Cavalheri, Vinicius, et al.
Published: (2014)

Modelling primary blast lung injury
by: Scott, Timothy E.
Published: (2020)

Phenotypic characterization of breast cancer: the role of CDC42
by: Chrysanthou, Eleni, et al.
Published: (2017)

Quantifying important risk factors and survival following treatment in people with lung cancer using routinely collected national data
by: Powell, Helen.
Published: (2014)

HTR4 gene structure and altered expression in the developing lung
by: Hodge, Emily, et al.
Published: (2013)

Investigating lung function gene GSTCD using gene targeting in human and mouse systems
by: Probert, Kelly
Published: (2016)

Validation of the National Lung Cancer Audit database and analysis of the information it contains
by: Rich, Anna
Published: (2012)

Lung cancer stage-shift following a symptom awareness campaign
by: Kennedy, Martyn, et al.
Published: (2018)

Formulation and optimization of nanoemulsion containing gemcitabine for lung cancer treatment
by: Wahgiman, Nadiatul Atiqah
Published: (2019)

Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways
by: Kheirallah, Alexander K., et al.
Published: (2017)

Airway pressure release ventilation mode in lung injury
by: Al-Ahmad, Abdullmohsen Mohammed
Published: (2017)

Biomarkers of progressive lung fibrosis
by: Khan, Fasihul
Published: (2022)

Advanced lung imaging and lung function testing in Ataxia-Telangiectasia
by: Alenazi, Saleh
Published: (2023)

CLASS B0445+123: a new two-image gravitational lens system
by: Argo, Megan, et al.
Published: (2003)

Lung cancer diagnosed following an emergency admission: mixed methods study of the management, outcomes and needs and experiences of patients and carers
by: Wilcock, Andrew, et al.
Published: (2016)

Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs
by: Tanino, Y., et al.
Published: (2010)

The emotional impact of screening for lung cancer
by: Bedford, Laura Elizabeth
Published: (2017)

The Ser82 RAGE variant affects lung function and serum RAGE in smokers and sRAGE production in vitro
by: Miller, Suzanne, et al.
Published: (2016)

Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of dams (female mice)
by: Smoothy, J., et al.
Published: (2019)

What characteristics of primary care and patients are associated with early death in patients with lung cancer in the UK?
by: O'Dowd, Emma L., et al.
Published: (2015)

The impact of the ‘hub and spoke’ model of care for lung cancer and equitable access to surgery
by: Khakwani, Aamir, et al.
Published: (2014)

Study on Liposomes Integrity and Delivery of siRNA to Lung Cancer
by: Aljasser, Abdullah
Published: (2024)

Understanding the Lung Disposition of Inhaled Compounds using the Bronchial Epithelial Cell Culture Model Calu-3
by: Panduga, Vijender
Published: (2019)