A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine

QR Code

A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine

Total syntheses of alkaloid cis-223B and xenovenine are reported in 3 and 4 steps respectively using a two-directional synthesis/triple reductive amination strategy, and their neurotoxic properties assessed.

Bibliographic Details
Main Authors:	Barthelme, Alexandre, Richards, David, Mellor, Ian R., Stockman, Robert A.
Format:	Article
Language:	English
Published:	Royal Society of Chemistry 2013
Online Access:	https://eprints.nottingham.ac.uk/35316/

Similar Items

Two-directional synthesis and biological evaluation of alkaloid 5-epi-cis-275B′
by: Procopiou, George, et al.
Published: (2014)

Analysis of pyrrolizidine alkaloids in stingless bee honey and identification of a botanical source as Ageratum conyzoides
by: Hungerford, Natasha L., et al.
Published: (2024)

Analysis of pyrrolizidine alkaloids in stingless bee honey and identification of a botanical source as Ageratum conyzoides
by: Hungerford, Natasha L., et al.
Published: (2024)

Anticancer properties and biological evaluation of natural alkaloid jerantinine B
by: Qazzaz, Mohannad Emad
Published: (2017)

In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B
by: Qazzaz, Mohannad E., et al.
Published: (2016)

Syntheses and structure-activity relationship studies of schwarzinicine alkaloids as vasorelaxant agents
by: Lee, Fong Kai
Published: (2020)

Studies towards the total synthesis of a natural product alkaloid
by: Walker, Hetty Sadie
Published: (2023)

Alkaloids from alphonsea elliptica barks and their biological activities
by: Obaid, Ahmed Kareem, et al.
Published: (2018)

Investigating ladybird alkaloids as potential leads for novel insecticides
by: Richards, David Philip
Published: (2016)

Total syntheses of shizukaols A and E
by: Wu, Jian-Li, et al.
Published: (2018)

Biological characterisation of a novel and naturally isolated indole alkaloid
by: Raja, Vijay J.
Published: (2015)

Biologically active indole and bisindole alkaloids from Tabernaemontana divaricata
by: Kam, Toh-Seok, et al.
Published: (2003)

Biologically active alkaloids from kopsia / Yap Wai Sum.
by: Yap, Wai Sum
Published: (2011)

JIB 223 – Cell Biology and Genetics [Biologi Sel dan Genetik]
by: PPJJ, Pusat Pengajian Jarak Jauh
Published: (2016)

JIB 223 – Cell Biology and Genetics [Biologi Sel dan Genetik]
by: PPJJ, Pusat Pengajian Jarak Jauh
Published: (2017)

JIB223 – Cell Biology and Genetics [Biologi Sel dan Genetik]
by: PPJJ, Pusat Pengajian Jarak Jauh
Published: (2018)

trans–cis S-Benzyl dithiocarbazate
by: Shanmuga Sundara Raj, S., et al.
Published: (2000)

Biologically active alkaloids from Alstonia angustiloba / Ku Wai Foong
by: Ku, Wai Foong
Published: (2011)

Characterisation and Biological Activities of Tinospora Crispa (Menispermaceae) Extract with Emphasis on Alkaloids
by: Azrulrizawati, Abd Hamid
Published: (2013)

Vinca alkaloids
by: Moudi, Maryam, et al.
Published: (2013)

Phytochemical content in Polyalthia bullata king and the effect of auxins, elicitors and precursors on total alkaloid content in callus
by: Kamarul Zaman, Munirah Adibah
Published: (2020)

Biologically active indole and bisindole alkaloids from Leuconotis and Kopsia / Gan Chew Yan
by: Gan, Chew Yan
Published: (2013)

Genome-wide computational identification of biologically significant cis-regulatory elements and associated transcription factors from rice
by: Ho, Chai Ling, et al.
Published: (2019)

CIS311 - Komunikasi Data November 1995
by: PPSKOM, Pusat Pengajian Sains Komputer
Published: (1995)

Semisynthesis of jerantinine alkaloids
by: Stanley, Paul
Published: (2017)

Total Synthesis of jerantinine alkaloids and a biocatalytic synthesis of 2,6 - Disubstituted tetrahydropyrans using an alcohol dehydrogenase
by: Eastman, H
Published: (2020)

Mini Review: Biologically synthesized nanoparticles as antifungal agents
by: Siti Nur Amalina, M. S., et al.
Published: (2021)

Alkaloid Constituents of haplophyllum laeviusculum(Rutaceae)(Kandungan alkaloid daripada haplophyllum laeviusculum (Rutaceae)
by: Parimah Parhoodeh,, et al.
Published: (2012)

Cis-clerodane-type furanoditerpenoids from Tinospora crispa
by: Choudhary, Muhammad Iqbal, et al.
Published: (2010)

CIS301 - PENGURUSAN SISTEM MAKLUMAT - NOV. 1995
by: PPSKOM, Pusat Pengajian Sains Komputer
Published: (1995)

CIS 311 - KOMUNIKASI DATA OKT-NOV 1995.
by: PPSKOM, Pusat Pengajian Sains Komputer
Published: (1995)

CIS 401 - DATABASE MANAGEMENT AND DESIGN SEPT 1997.
by: PPSKOM, Pusat Pengajian Sains Komputer
Published: (1997)

CIS301 - Pengurusan Sistem Maklumat November 1995
by: PPSKOM, Pusat Pengajian Sains Komputer
Published: (1995)

Alkaloidal constituents of Tinospora crispa
by: Choudhary, M. Iqbal, et al.
Published: (2010)

Plant toxins: alkaloids and their toxicities
by: Mohamad Azzeme, Azzreena, et al.
Published: (2019)

The alkaloids of Ophiorrhiza cf. ferruginea
by: Arbain, Dayar, et al.
Published: (1993)

English version of Elderly-Constipation Impact Scale (E-CIS)
by: Abdul Wahab, Patimah, et al.
Published: (2019)

CIS 301 - PENGURUSAN SISTEM MAKLUMAT OKT-NOV 1995.
by: PPSKOM, Pusat Pengajian Sains Komputer
Published: (1995)

CIS 301 - PENGURUSAN SISTEM MAKLUMAT OKT-NOV 1996.
by: PPSKOM, Pusat Pengajian Sains Komputer
Published: (1996)

CIS 401 - DATABASE MANAGEMENT AND DESIGN OCT-NOV 1996.
by: PPSKOM, Pusat Pengajian Sains Komputer
Published: (1996)