A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine
Total syntheses of alkaloid cis-223B and xenovenine are reported in 3 and 4 steps respectively using a two-directional synthesis/triple reductive amination strategy, and their neurotoxic properties assessed.
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Royal Society of Chemistry
2013
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| Online Access: | https://eprints.nottingham.ac.uk/35316/ |
| _version_ | 1848795050348118016 |
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| author | Barthelme, Alexandre Richards, David Mellor, Ian R. Stockman, Robert A. |
| author_facet | Barthelme, Alexandre Richards, David Mellor, Ian R. Stockman, Robert A. |
| author_sort | Barthelme, Alexandre |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Total syntheses of alkaloid cis-223B and xenovenine are reported in 3 and 4 steps respectively using a two-directional synthesis/triple reductive amination strategy, and their neurotoxic properties assessed. |
| first_indexed | 2025-11-14T19:25:55Z |
| format | Article |
| id | nottingham-35316 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T19:25:55Z |
| publishDate | 2013 |
| publisher | Royal Society of Chemistry |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-353162017-10-13T16:57:19Z https://eprints.nottingham.ac.uk/35316/ A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine Barthelme, Alexandre Richards, David Mellor, Ian R. Stockman, Robert A. Total syntheses of alkaloid cis-223B and xenovenine are reported in 3 and 4 steps respectively using a two-directional synthesis/triple reductive amination strategy, and their neurotoxic properties assessed. Royal Society of Chemistry 2013-11-18 Article PeerReviewed application/pdf en cc_by https://eprints.nottingham.ac.uk/35316/1/ChemComm%202013.pdf Barthelme, Alexandre, Richards, David, Mellor, Ian R. and Stockman, Robert A. (2013) A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine. Chemical Communications, 49 (89). pp. 10507-10509. ISSN 1364-548X http://pubs.rsc.org/en/Content/ArticleLanding/2013/CC/c3cc46800c#!divAbstract doi:10.1039/c3cc46800c doi:10.1039/c3cc46800c |
| spellingShingle | Barthelme, Alexandre Richards, David Mellor, Ian R. Stockman, Robert A. A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine |
| title | A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine |
| title_full | A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine |
| title_fullStr | A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine |
| title_full_unstemmed | A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine |
| title_short | A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine |
| title_sort | two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223b and (+/-)-xenovenine |
| url | https://eprints.nottingham.ac.uk/35316/ https://eprints.nottingham.ac.uk/35316/ https://eprints.nottingham.ac.uk/35316/ |