Mitochondrial complex 1 activity measured by spectrophotometry is reduced across all brain regions in ageing and more specifically in neurodegeneration

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Mitochondrial complex 1 activity measured by spectrophotometry is reduced across all brain regions in ageing and more specifically in neurodegeneration

Mitochondrial function, in particular complex 1 of the electron transport chain (ETC), has been shown to decrease during normal ageing and in neurodegenerative disease. However, there is some debate concerning which area of the brain has the greatest complex 1 activity. It is important to identify t...

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Bibliographic Details
Main Authors:	Cai, Huaibin, Pollard, Amelia Kate, Craig, Emma Louise, Chakrabarti, Lisa
Format:	Article
Published:	Public Library of Science 2016
Online Access:	https://eprints.nottingham.ac.uk/35300/

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