Immunocompetent 3D Model of Human Upper Airway for Disease Modeling and In Vitro Drug Evaluation

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Immunocompetent 3D Model of Human Upper Airway for Disease Modeling and In Vitro Drug Evaluation

The development of more complex in vitro models for the assessment of novel drugs and chemicals is needed because of the limited biological relevance of animal models to humans as well as ethical considerations. Although some human-cell-based assays exist, they are usually 2D, consist of single cell...

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Bibliographic Details
Main Authors:	Harrington, Helen, Cato, Paul, Salazar, Fabian, Wilkinson, Malcolm, Knox, Alan, Haycock, John W., Rose, Felicity R.A.J., Aylott, Jonathan W., Ghaemmaghami, Amir M.
Format:	Article
Published:	American Chemical Society 2014
Subjects:	Lung 3D scaffold coculture triculture immune cells electrospinning dendritic cells allergy
Online Access:	https://eprints.nottingham.ac.uk/35149/

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