Kinetic analysis of antagonist-occupied adenosine-A3 receptors within membrane microdomains of individual cells provides evidence of receptor dimerization and allosterism
In our previous work, using a fluorescent adenosine-A3 receptor (A3AR) agonist and fluorescence correlation spectroscopy (FCS), we demonstrated high-affinity labeling of the active receptor (R*) conformation. In the current study, we used a fluorescent A3AR antagonist (CA200645) to study the binding...
| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
Federation of American Society of Experimental Biology
2014
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/35147/ |