Direct visualisation of internalization of the adenosine A3 receptor and localization with arrestin3 using a fluorescent agonist

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Direct visualisation of internalization of the adenosine A3 receptor and localization with arrestin3 using a fluorescent agonist

Fluorescence based probes provide a novel way to study the dynamic internalization process of G protein-coupled receptors (GPCRs). Recent advances in the rational design of fluorescent ligands for GPCRs have been used here to generate new fluorescent agonists containing tripeptide linkers for the ad...

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Bibliographic Details
Main Authors:	Stoddart, Leigh A., Vernall, Andrea J., Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.
Format:	Article
Published:	Elsevier 2015
Subjects:	Adenosine receptors; Adenosine A3 receptor; Fluorescent agonist; Internalization; Arrestin3
Online Access:	https://eprints.nottingham.ac.uk/35144/

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