The role of Cas8 in type I CRISPR interference
CRISPR (clustered regularly interspaced short palindromic repeat) systems provide bacteria and archaea with adapt- ive immunity to repel invasive genetic elements. Type I systems use ‘cascade’ [CRISPR-associated (Cas) complex for antiviral defence] ribonucleoprotein complexes to target invader DNA,...
| Main Authors: | Cass, Simon, Haas, Karina, Stoll, Britta, Alkhnbashi, Omer, Sharma, Kundan, Urlaub, Henning, Backofen, Rolf, Marchfelder, Anita, Bolt, Edward |
|---|---|
| Format: | Article |
| Published: |
Portland Press
2015
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/35112/ |
Similar Items
Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3
by: Gong, Bei, et al.
Published: (2014)
by: Gong, Bei, et al.
Published: (2014)
CRISPR-Cas9-mediated genome editing of the extracellular matrix gene TNC in human fibroblasts
by: Brunetti, Giulio
Published: (2017)
by: Brunetti, Giulio
Published: (2017)
CRISPR-Cas immunity: analysis of adaptation and interference reactions in prokaryotes
by: Cass, S.D.B.
Published: (2016)
by: Cass, S.D.B.
Published: (2016)
RNA-guided integration of diverse DNA molecules by casposase-Cas9 fusions
by: Lau, Chun H.
Published: (2020)
by: Lau, Chun H.
Published: (2020)
Investigation of CRISPR-Cas adaptation mechanism through exploration of Cas4-1 fusions
by: Walker, Emily
Published: (2019)
by: Walker, Emily
Published: (2019)
Characterising Host Factors Required for CRISPR Cas Adaptation in Escherichia coli
by: Edwards, Harry
Published: (2023)
by: Edwards, Harry
Published: (2023)
Investigating a human DNA repair helicase that supports CRISPR editing
by: Cubbon, Andrew
Published: (2022)
by: Cubbon, Andrew
Published: (2022)
Analysis of the E. coli CRISPR Cas3 protein and its potential for regulation by a short non-coding RNA
by: Kennerdale, Niamh
Published: (2024)
by: Kennerdale, Niamh
Published: (2024)
Cas3 nuclease activity is regulated by an iHDA1 region located at the interface between HD and RecA1 domain
by: He, Liu
Published: (2022)
by: He, Liu
Published: (2022)
Part A: Application of fluorescent markers onto CRISPR-associated proteins/ Part B: Substitution of cysteine residues in CRISPR associated Protein Cas1
by: Parr, Lochlan
Published: (2024)
by: Parr, Lochlan
Published: (2024)
CRISPR-Cas9 gene targeting of human induced pluripotent stem cells to generate a palette of optical reporter cell lines towards investigating hypertrophic cardiomyopathy
by: Bhagwan, Jamie R.
Published: (2018)
by: Bhagwan, Jamie R.
Published: (2018)
Cas3 is a limiting factor for CRISPR-Cas immunity in Escherichia coli cells lacking H-NS
by: Majsec, Kristina, et al.
Published: (2016)
by: Majsec, Kristina, et al.
Published: (2016)
Genetic screens in intestinal organoid (mini-gut) culture using CRISPR-Cas-9 System and studying the role of FBXL5 in colorectal cancer cells
by: Jinks, Nicholas
Published: (2022)
by: Jinks, Nicholas
Published: (2022)
Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development
by: Ghosh, Tushar K., et al.
Published: (2018)
by: Ghosh, Tushar K., et al.
Published: (2018)
Development of a high-throughput screen for the study of CRISPR spacer acquisition
by: Braithwaite, Jack
Published: (2021)
by: Braithwaite, Jack
Published: (2021)
Analysis of Cas1-2 and Cas3 CRISPR immunity proteins in
E. coli cell physiology
by: Reeves, Ryan Peter
Published: (2019)
by: Reeves, Ryan Peter
Published: (2019)
Exploiting acetogenic bacteria for sustainable production of chemicals
by: Poulalier Delavelle, Margaux
Published: (2023)
by: Poulalier Delavelle, Margaux
Published: (2023)
Simplified footprint-free Cas9/CRISPR editing of cardiac-associated genes in human pluripotent stem cells
by: Kondrashov, Alexander, et al.
Published: (2018)
by: Kondrashov, Alexander, et al.
Published: (2018)
Development of molecular tools for optimisation of C1 gas fermentation in acetogens
by: Rowe, Peter
Published: (2018)
by: Rowe, Peter
Published: (2018)
The bacteriophage carrier state of Campylobacter jejuni features changes in host non-coding RNAs and the acquisition of new host-derived CRISPR spacer sequences
by: Hooton, Steven P.T., et al.
Published: (2016)
by: Hooton, Steven P.T., et al.
Published: (2016)
Understanding the pathogenesis and potential therapeutics of Myotonic dystrophy
by: Verma, Ayushri
Published: (2024)
by: Verma, Ayushri
Published: (2024)
Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs
by: Bertero, Alessandro, et al.
Published: (2016)
by: Bertero, Alessandro, et al.
Published: (2016)
Disease modeling hypertrophic cardiomyopathy using CRISPR/Cas9 genome editing technology in human pluripotent stem cell-derived cardiomyocytes
by: Mosqueira, Diogo
Published: (2018)
by: Mosqueira, Diogo
Published: (2018)
CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy
by: Mosqueira, Diogo, et al.
Published: (2018)
by: Mosqueira, Diogo, et al.
Published: (2018)
Development of Genetic Tools for the Chemolithoautotroph C. metallidurans CH34: Harnessing Synthetic Biology to Expand Knowledge of Extracellular Electron Transfer
by: Turco, Federico
Published: (2022)
by: Turco, Federico
Published: (2022)
Linking molecular targets to hypertrophic cardiomyopathy using genome-edited human induced pluripotent stem cell cardiomyocytes
by: Bodbin, S.E.
Published: (2022)
by: Bodbin, S.E.
Published: (2022)
Development of forward and reverse genetic tools for
Eubacterium limosum
by: Millard, Christopher
Published: (2018)
by: Millard, Christopher
Published: (2018)
Developments in genetic engineering of novel acetogens
by: Mansfield, Robert Patrick William
Published: (2018)
by: Mansfield, Robert Patrick William
Published: (2018)
Gene editing the phytoene desaturase alleles of Cavendish banana using CRISPR/Cas9
by: Eftekhari, Fatima, et al.
Published: (2018)
by: Eftekhari, Fatima, et al.
Published: (2018)
Using human induced pluripotent stem cells to study the in vitro phenotype of the cardiac channelopathies
by: Duncan, Gary
Published: (2017)
by: Duncan, Gary
Published: (2017)
The relationship of CDK18 expression in breast cancer to clinicopathological parameters and therapeutic response
by: Barone, Giancarlo, et al.
Published: (2018)
by: Barone, Giancarlo, et al.
Published: (2018)
Expansion of the genome editing toolbox of Clostridium autoethanogenum
by: Seys, François M.
Published: (2022)
by: Seys, François M.
Published: (2022)
Investigating genome engineering of myotonic dystrophy cells and small molecules as potential therapeutic agents
by: López Morató, Marta
Published: (2018)
by: López Morató, Marta
Published: (2018)
Structure-Function analysis of a novel DNA-binding domain of the histone acetyltransferase MOZ/KAT6A
by: Schoenfeld, Jonas
Published: (2019)
by: Schoenfeld, Jonas
Published: (2019)
Studying novel sporulation genes in Clostridium sporogenes
by: Rizvi, Syeda-Rubab-Zehra
Published: (2020)
by: Rizvi, Syeda-Rubab-Zehra
Published: (2020)
Palindromes in circular words
by: Simpson, Jamie
Published: (2014)
by: Simpson, Jamie
Published: (2014)
Applications of a high-throughput screen detecting CRISPR-Cas spacer acquisition
by: Cannon, Christopher
Published: (2025)
by: Cannon, Christopher
Published: (2025)
Adults in Perlis have to do night patrols
Published: (2008)
Published: (2008)
Learned changes in outcome associability
by: Quigley, Martyn C., et al.
Published: (2017)
by: Quigley, Martyn C., et al.
Published: (2017)
Can human pluripotent stem cell-derived cardiomyocytes advance understanding of muscular dystrophies?
by: Kalra, Spandan, et al.
Published: (2016)
by: Kalra, Spandan, et al.
Published: (2016)
Similar Items
-
Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3
by: Gong, Bei, et al.
Published: (2014) -
CRISPR-Cas9-mediated genome editing of the extracellular matrix gene TNC in human fibroblasts
by: Brunetti, Giulio
Published: (2017) -
CRISPR-Cas immunity: analysis of adaptation and interference reactions in prokaryotes
by: Cass, S.D.B.
Published: (2016) -
RNA-guided integration of diverse DNA molecules by casposase-Cas9 fusions
by: Lau, Chun H.
Published: (2020) -
Investigation of CRISPR-Cas adaptation mechanism through exploration of Cas4-1 fusions
by: Walker, Emily
Published: (2019)