Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain

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Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain

Objectives Blockade of transient receptor potential vanilloid 1 (TRPV1) with systemic antagonists attenuates osteoarthritis (OA) pain behaviour in rat models, but on-target-mediated hyperthermia has halted clinical trials. The present study investigated the potential for targeting TRPV1 receptors wi...

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Bibliographic Details
Main Authors:	Kelly, Sara, Chapman, R.J., Woodhams, S., Sagar, Devi Rani, Turner, J., Burston, J.J., Bullock, C., Paton, K., Huang, J., Wong, A., McWilliams, D.F., Okine, B.N., Barrett, D.A., Hathway, G.J., Walsh, D.A., Chapman, V.
Format:	Article
Published:	European League Against Rheumatism (EULAR) and BMJ 2013
Online Access:	https://eprints.nottingham.ac.uk/35039/

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