Periaqueductal grey EP3 receptors facilitate spinal nociception in arthritic secondary hypersensitivity

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Periaqueductal grey EP3 receptors facilitate spinal nociception in arthritic secondary hypersensitivity

Descending controls on spinal nociceptive processing play a pivotal role in shaping the pain experience following tissue injury. Secondary hypersensitivity develops within undamaged tissue adjacent, and distant to, damaged sites. Spinal neuronal pools innervating regions of secondary hypersensitivit...

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Bibliographic Details
Main Authors:	Drake, Robert A.R., Leith, J.L., Almahasneh, F., Martindale, J., Wilson, A.W., Lumb, B.M., Donaldson, Lucy F.
Format:	Article
Published:	Society for Neuroscience 2016
Subjects:	Arthritis Descending Facilitation Inflammation Periaqueductal grey Prostaglandins Secondary Hyperalgesia
Online Access:	https://eprints.nottingham.ac.uk/34730/

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