Cohort profile: the Flu Watch Study
Influenza is a common, highly contagious respiratory virus which infects all age groups, causing a range of outcomes from asymptomatic infection and mild respiratory disease to severe respiratory disease and death.1 If infected, the adaptive immune system produces a humoral (antibody) and cell-media...
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| Format: | Article |
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Oxford University Press
2016
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| Online Access: | https://eprints.nottingham.ac.uk/34691/ |
| _version_ | 1848794913127268352 |
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| author | Fragaszy, Ellen B. Warren-Gash, Charlotte Wang, Lili Copas, Andrew Dukes, Oliver Edmunds, W. John Goonetilleke, Nile Harvey, Gabrielle Johnson, Anne M. Kovar, Jana Lim, Megan S.C. McMichael, Andrew Millett, Elizabeth R.C. Nazareth, Irwin Nguyen-Van-Tam, Jonathan Tabassum, Faiza Watson, John M. Wurie, Fatima Zambon, Maria Hayward, Andrew C. |
| author_facet | Fragaszy, Ellen B. Warren-Gash, Charlotte Wang, Lili Copas, Andrew Dukes, Oliver Edmunds, W. John Goonetilleke, Nile Harvey, Gabrielle Johnson, Anne M. Kovar, Jana Lim, Megan S.C. McMichael, Andrew Millett, Elizabeth R.C. Nazareth, Irwin Nguyen-Van-Tam, Jonathan Tabassum, Faiza Watson, John M. Wurie, Fatima Zambon, Maria Hayward, Andrew C. |
| author_sort | Fragaszy, Ellen B. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Influenza is a common, highly contagious respiratory virus which infects all age groups, causing a range of outcomes from asymptomatic infection and mild respiratory disease to severe respiratory disease and death.1 If infected, the adaptive immune system produces a humoral (antibody) and cell-mediated (T cell) immune response to fight the infection.2 Influenza viruses continually evolve through antigenic drift, resulting in slightly different ‘seasonal’ influenza strains circulating each year. Population-level antibody immunity to these seasonal viruses builds up over time, so in any given season only a proportion of the population is susceptible to the circulating strains. Occasionally, influenza A viruses evolve rapidly through antigenic shift by swapping genes with influenza viruses usually circulating in animals. This process creates an immunologically distinct virus to which the population may have little to no antibody immunity. The virus can result in a pandemic if a large portion of the population is susceptible and the virus is easily spread. |
| first_indexed | 2025-11-14T19:23:44Z |
| format | Article |
| id | nottingham-34691 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:23:44Z |
| publishDate | 2016 |
| publisher | Oxford University Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-346912020-05-04T17:42:58Z https://eprints.nottingham.ac.uk/34691/ Cohort profile: the Flu Watch Study Fragaszy, Ellen B. Warren-Gash, Charlotte Wang, Lili Copas, Andrew Dukes, Oliver Edmunds, W. John Goonetilleke, Nile Harvey, Gabrielle Johnson, Anne M. Kovar, Jana Lim, Megan S.C. McMichael, Andrew Millett, Elizabeth R.C. Nazareth, Irwin Nguyen-Van-Tam, Jonathan Tabassum, Faiza Watson, John M. Wurie, Fatima Zambon, Maria Hayward, Andrew C. Influenza is a common, highly contagious respiratory virus which infects all age groups, causing a range of outcomes from asymptomatic infection and mild respiratory disease to severe respiratory disease and death.1 If infected, the adaptive immune system produces a humoral (antibody) and cell-mediated (T cell) immune response to fight the infection.2 Influenza viruses continually evolve through antigenic drift, resulting in slightly different ‘seasonal’ influenza strains circulating each year. Population-level antibody immunity to these seasonal viruses builds up over time, so in any given season only a proportion of the population is susceptible to the circulating strains. Occasionally, influenza A viruses evolve rapidly through antigenic shift by swapping genes with influenza viruses usually circulating in animals. This process creates an immunologically distinct virus to which the population may have little to no antibody immunity. The virus can result in a pandemic if a large portion of the population is susceptible and the virus is easily spread. Oxford University Press 2016-03-03 Article PeerReviewed Fragaszy, Ellen B., Warren-Gash, Charlotte, Wang, Lili, Copas, Andrew, Dukes, Oliver, Edmunds, W. John, Goonetilleke, Nile, Harvey, Gabrielle, Johnson, Anne M., Kovar, Jana, Lim, Megan S.C., McMichael, Andrew, Millett, Elizabeth R.C., Nazareth, Irwin, Nguyen-Van-Tam, Jonathan, Tabassum, Faiza, Watson, John M., Wurie, Fatima, Zambon, Maria and Hayward, Andrew C. (2016) Cohort profile: the Flu Watch Study. International Journal of Epidemiology . ISSN 0300-5771 http://ije.oxfordjournals.org/content/early/2016/03/02/ije.dyv370 doi:10.1093/ije/dyv370 doi:10.1093/ije/dyv370 |
| spellingShingle | Fragaszy, Ellen B. Warren-Gash, Charlotte Wang, Lili Copas, Andrew Dukes, Oliver Edmunds, W. John Goonetilleke, Nile Harvey, Gabrielle Johnson, Anne M. Kovar, Jana Lim, Megan S.C. McMichael, Andrew Millett, Elizabeth R.C. Nazareth, Irwin Nguyen-Van-Tam, Jonathan Tabassum, Faiza Watson, John M. Wurie, Fatima Zambon, Maria Hayward, Andrew C. Cohort profile: the Flu Watch Study |
| title | Cohort profile: the Flu Watch Study |
| title_full | Cohort profile: the Flu Watch Study |
| title_fullStr | Cohort profile: the Flu Watch Study |
| title_full_unstemmed | Cohort profile: the Flu Watch Study |
| title_short | Cohort profile: the Flu Watch Study |
| title_sort | cohort profile: the flu watch study |
| url | https://eprints.nottingham.ac.uk/34691/ https://eprints.nottingham.ac.uk/34691/ https://eprints.nottingham.ac.uk/34691/ |