Psychosocial interventions following self-harm in adults: a systematic review and meta-analysis

Background: Self-harm (intentional acts of non-fatal self-poisoning or self-injury) is common, often repeated and strongly associated with suicide. Effective aftercare of individuals who self-harm is therefore important. We have undertaken a Cochrane systematic review and meta-analysis of the effect...

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Main Authors: Hawton, Keith, Witt, Katrina G., Taylor Salisbury, Tatiana L., Arensman, Ella, Gunnell, David, Hazell, Philip, Townsend, Ellen, van Heeringen, Kees
Format: Article
Published: Elsevier 2016
Online Access:https://eprints.nottingham.ac.uk/34637/
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author Hawton, Keith
Witt, Katrina G.
Taylor Salisbury, Tatiana L.
Arensman, Ella
Gunnell, David
Hazell, Philip
Townsend, Ellen
van Heeringen, Kees
author_facet Hawton, Keith
Witt, Katrina G.
Taylor Salisbury, Tatiana L.
Arensman, Ella
Gunnell, David
Hazell, Philip
Townsend, Ellen
van Heeringen, Kees
author_sort Hawton, Keith
building Nottingham Research Data Repository
collection Online Access
description Background: Self-harm (intentional acts of non-fatal self-poisoning or self-injury) is common, often repeated and strongly associated with suicide. Effective aftercare of individuals who self-harm is therefore important. We have undertaken a Cochrane systematic review and meta-analysis of the effectiveness of psychosocial interventions for self-harm in adults. Methods: We searched five electronic databases (CCDANCTR-Studies and References, CENTRAL, MEDLINE, EMBASE, and PsycINFO) for randomised controlled trials (RCTs) of psychosocial interventions for adults following a recent (within six months) episode of self-harm. Fifty-five non-overlapping RCTs were identified. Most interventions were evaluated in single trials. We report results for interventions for which at least three RCTs comparing interventions to treatment as usual have been published and hence might contribute to clinical guidance. Findings: Cognitive behavioural-based psychotherapy (CBT; comprising cognitive-behavioural and/or problem-solving therapy) was associated with fewer participants repeating self-harm at six (OR 0·54, 95% CI 0·34 to 0·85; 12 trials; N=1,317) and 12 months’ follow-up (OR 0·80, 95% CI 0·65 to 0·98; 10 trials; N=2,142). There were also significant improvements in depression, hopelessness and suicidal ideation. Patients receiving dialectical behaviour therapy (DBT; three trials) had fewer repeat self-harm episodes post-intervention (MD -18·80, 95% CI -36·70 – -0·95; 3 trials; N=292), however, DBT was not associated with a significant reduction in the proportion of participants engaging in self-harm. Case management and sending regular postcards (four trials each) did not reduce repetition. Interpretation: CBT-based psychotherapy appears to be effective in patients following self-harm. DBT reduces frequency of repetition of self-harm. However, aside for CBT-based psychotherapy, there were few trials of other promising interventions, precluding firm conclusions as to their effectiveness.
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spelling nottingham-346372020-05-04T17:58:20Z https://eprints.nottingham.ac.uk/34637/ Psychosocial interventions following self-harm in adults: a systematic review and meta-analysis Hawton, Keith Witt, Katrina G. Taylor Salisbury, Tatiana L. Arensman, Ella Gunnell, David Hazell, Philip Townsend, Ellen van Heeringen, Kees Background: Self-harm (intentional acts of non-fatal self-poisoning or self-injury) is common, often repeated and strongly associated with suicide. Effective aftercare of individuals who self-harm is therefore important. We have undertaken a Cochrane systematic review and meta-analysis of the effectiveness of psychosocial interventions for self-harm in adults. Methods: We searched five electronic databases (CCDANCTR-Studies and References, CENTRAL, MEDLINE, EMBASE, and PsycINFO) for randomised controlled trials (RCTs) of psychosocial interventions for adults following a recent (within six months) episode of self-harm. Fifty-five non-overlapping RCTs were identified. Most interventions were evaluated in single trials. We report results for interventions for which at least three RCTs comparing interventions to treatment as usual have been published and hence might contribute to clinical guidance. Findings: Cognitive behavioural-based psychotherapy (CBT; comprising cognitive-behavioural and/or problem-solving therapy) was associated with fewer participants repeating self-harm at six (OR 0·54, 95% CI 0·34 to 0·85; 12 trials; N=1,317) and 12 months’ follow-up (OR 0·80, 95% CI 0·65 to 0·98; 10 trials; N=2,142). There were also significant improvements in depression, hopelessness and suicidal ideation. Patients receiving dialectical behaviour therapy (DBT; three trials) had fewer repeat self-harm episodes post-intervention (MD -18·80, 95% CI -36·70 – -0·95; 3 trials; N=292), however, DBT was not associated with a significant reduction in the proportion of participants engaging in self-harm. Case management and sending regular postcards (four trials each) did not reduce repetition. Interpretation: CBT-based psychotherapy appears to be effective in patients following self-harm. DBT reduces frequency of repetition of self-harm. However, aside for CBT-based psychotherapy, there were few trials of other promising interventions, precluding firm conclusions as to their effectiveness. Elsevier 2016-08-01 Article PeerReviewed Hawton, Keith, Witt, Katrina G., Taylor Salisbury, Tatiana L., Arensman, Ella, Gunnell, David, Hazell, Philip, Townsend, Ellen and van Heeringen, Kees (2016) Psychosocial interventions following self-harm in adults: a systematic review and meta-analysis. The Lancet Psychiatry, 3 (8). pp. 740-750. ISSN 2215-0366 http://thelancet.com/journals/lanpsy/article/PIIS2215-0366(16)30070-0/fulltext doi:10.1016/S2215-0366(16)30070-0 doi:10.1016/S2215-0366(16)30070-0
spellingShingle Hawton, Keith
Witt, Katrina G.
Taylor Salisbury, Tatiana L.
Arensman, Ella
Gunnell, David
Hazell, Philip
Townsend, Ellen
van Heeringen, Kees
Psychosocial interventions following self-harm in adults: a systematic review and meta-analysis
title Psychosocial interventions following self-harm in adults: a systematic review and meta-analysis
title_full Psychosocial interventions following self-harm in adults: a systematic review and meta-analysis
title_fullStr Psychosocial interventions following self-harm in adults: a systematic review and meta-analysis
title_full_unstemmed Psychosocial interventions following self-harm in adults: a systematic review and meta-analysis
title_short Psychosocial interventions following self-harm in adults: a systematic review and meta-analysis
title_sort psychosocial interventions following self-harm in adults: a systematic review and meta-analysis
url https://eprints.nottingham.ac.uk/34637/
https://eprints.nottingham.ac.uk/34637/
https://eprints.nottingham.ac.uk/34637/