Low alpha-defensin gene copy number increases the risk for IgA nephropathy and renal dysfunction

Low alpha-defensin gene copy number increases the risk for IgA nephropathy and renal dysfunction

IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. Although a major source of genetic variation, copy number variations (CNVs) and their involvement in disease development have not been well studied. Here, we performed association analysis of the DEFA1A3 CNV locus in two...

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Bibliographic Details
Main Authors: Ai, Zhen, Li, Ming, Liu, Wenting, Foo, Jia-Nee, Mansouri, Omniah, Yin, Peiran, Zhou, Qian, Tang, Xueqing, Dong, Xiuqing, Feng, Shaozhen, Xu, Ricong, Zhong, Zhong, Chen, Jian, Wan, Jianxin, Lou, Tanqi, Yu, Jianwen, Zhou, Qin, Fan, Jinjin, Mao, Haiping, Gale, Daniel, Barratt, Jonathan, Armour, John A.L., Liu, Jianjun, Yu, Xueqing
Format: Article
Published: American Association for the Advancement of Science 2016
Online Access:https://eprints.nottingham.ac.uk/34556/

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