Novel gonadal characteristics in an aged bovine freemartin
The gonads from a five year old freemartin Holstein animal were subjected to morphological analysis and to immunohistochemistry using antibodies against developmental and functional markers. We demonstrate, for the first time, the retention of anti-mullerian hormone (AMH) producing intratubular cell...
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| Format: | Article |
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Elsevier
2014
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| Online Access: | https://eprints.nottingham.ac.uk/34519/ |
| _version_ | 1848794872682643456 |
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| author | Remnant, J.G. Lea, Richard G. Allen, Ceri E. Huxley, J.N. Robinson, Robert S. Brower, A. |
| author_facet | Remnant, J.G. Lea, Richard G. Allen, Ceri E. Huxley, J.N. Robinson, Robert S. Brower, A. |
| author_sort | Remnant, J.G. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | The gonads from a five year old freemartin Holstein animal were subjected to morphological analysis and to immunohistochemistry using antibodies against developmental and functional markers. We demonstrate, for the first time, the retention of anti-mullerian hormone (AMH) producing intratubular cells (Sertoli cells) in the context of abundant steroidogenic interstitial cells, and structures consistent with clusters of luteal cells. This novel report describes the clinical, gross and histological findings accompanying this newly described gonadal immunophenotype, and its implication in the understanding of freemartin development. |
| first_indexed | 2025-11-14T19:23:06Z |
| format | Article |
| id | nottingham-34519 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:23:06Z |
| publishDate | 2014 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-345192020-05-04T16:43:48Z https://eprints.nottingham.ac.uk/34519/ Novel gonadal characteristics in an aged bovine freemartin Remnant, J.G. Lea, Richard G. Allen, Ceri E. Huxley, J.N. Robinson, Robert S. Brower, A. The gonads from a five year old freemartin Holstein animal were subjected to morphological analysis and to immunohistochemistry using antibodies against developmental and functional markers. We demonstrate, for the first time, the retention of anti-mullerian hormone (AMH) producing intratubular cells (Sertoli cells) in the context of abundant steroidogenic interstitial cells, and structures consistent with clusters of luteal cells. This novel report describes the clinical, gross and histological findings accompanying this newly described gonadal immunophenotype, and its implication in the understanding of freemartin development. Elsevier 2014-04-01 Article PeerReviewed Remnant, J.G., Lea, Richard G., Allen, Ceri E., Huxley, J.N., Robinson, Robert S. and Brower, A. (2014) Novel gonadal characteristics in an aged bovine freemartin. Animal Reproduction Science, 146 (1-2). pp. 1-4. ISSN 1873-2232 Anti-Mullerian Hormone (AMH) Bovine CYP17A1 Freemartin Gonad http://www.sciencedirect.com/science/article/pii/S0378432014000517 doi:10.1016/j.anireprosci.2014.02.011 doi:10.1016/j.anireprosci.2014.02.011 |
| spellingShingle | Anti-Mullerian Hormone (AMH) Bovine CYP17A1 Freemartin Gonad Remnant, J.G. Lea, Richard G. Allen, Ceri E. Huxley, J.N. Robinson, Robert S. Brower, A. Novel gonadal characteristics in an aged bovine freemartin |
| title | Novel gonadal characteristics in an aged bovine freemartin |
| title_full | Novel gonadal characteristics in an aged bovine freemartin |
| title_fullStr | Novel gonadal characteristics in an aged bovine freemartin |
| title_full_unstemmed | Novel gonadal characteristics in an aged bovine freemartin |
| title_short | Novel gonadal characteristics in an aged bovine freemartin |
| title_sort | novel gonadal characteristics in an aged bovine freemartin |
| topic | Anti-Mullerian Hormone (AMH) Bovine CYP17A1 Freemartin Gonad |
| url | https://eprints.nottingham.ac.uk/34519/ https://eprints.nottingham.ac.uk/34519/ https://eprints.nottingham.ac.uk/34519/ |