Acyl hydrolases from trans-AT polyketide synthases target acetyl units on acyl carrier proteins
Acyl hydrolase (AH) domains are a common feature of trans-AT PKSs. They have been hypothesised to perform a proofreading function by removing acyl chains from stalled sites. This study determines the substrate tolerance of the AH PedC for a range of acyl-ACPs. Clear preference towards short, linear...
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Bibliographic Details
| Main Authors: |
Jenner, Matthew,
Afonso, José P.,
Kohlhaas, Christoph,
Karbaum, Petra,
Frank, Sarah,
Piel, Jörn,
Oldham, Neil J. |
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| Format: | Article
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| Published: |
Royal Society of Chemistry
2016
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| Online Access: | https://eprints.nottingham.ac.uk/34373/
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