Enantioselective nickel-catalyzed anti-carbometallative cyclizations
of alkynyl electrophiles enabled by reversible alkenylnickel E/Z
isomerization

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Enantioselective nickel-catalyzed anti-carbometallative cyclizations of alkynyl electrophiles enabled by reversible alkenylnickel E/Z isomerization

Nickel-catalyzed additions of arylboronic acids to alkynes, followed by enantioselective cyclizations of the alkenylnickel species onto tethered ketones or enones, are reported. These reactions are reliant upon the formal anti-carbonickelation of the alkyne, which is postulated to occur by the rever...

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Bibliographic Details
Main Authors:	Clarke, Christopher, Incerti-Pradillos, Celia A., Lam, Hon Wai
Format:	Article
Published:	American Chemical Society 2016
Online Access:	https://eprints.nottingham.ac.uk/34188/

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