Evaluation of immune cell infiltrates and expression of cytokines/biological molecules in the microenvironment of tumours and tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy: crucial contribution to immune-mediated tumour cell death

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Evaluation of immune cell infiltrates and expression of cytokines/biological molecules in the microenvironment of tumours and tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy: crucial contribution to immune-mediated tumour cell death

Background Neoadjuvant chemotherapy (NAC) is being used as first line treatment in women with large and locally advanced breast cancers (LLABCs). However, the response to NAC is difficult to predict. Growing evidence suggests that these patients are immunosuppressed and that circulating immunos...

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Bibliographic Details
Main Author:	Kaewkangsadan, Viriya
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Subjects:	Response to neoadjuvant chemotherapy Tumour microenvironment Immune-modulatory effects Immunosuppression
Online Access:	https://eprints.nottingham.ac.uk/34155/

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