Investigating the use of oligonucleotides for the treatment of muscular dystrophy

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Investigating the use of oligonucleotides for the treatment of muscular dystrophy

Antisense oligonucleotide therapy is one of the most promising strategies for treatment of myotonic dystrophy type 1 (DM1), type 2 (DM2) and Duchene muscular dystrophy (DMD). These three diseases have nuclear retained mRNA, suitable for antisense therapy targeting. The delivery of oligonucleotides...

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Bibliographic Details
Main Author:	Moore, Rebecca L. L.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Online Access:	https://eprints.nottingham.ac.uk/34150/

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