Refining adverse drug reaction signals by incorporating interaction variables identified using emergent pattern mining

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Refining adverse drug reaction signals by incorporating interaction variables identified using emergent pattern mining

Purpose: To develop a framework for identifying and incorporating candidate confounding interaction terms into a regularised cox regression analysis to refine adverse drug reaction signals obtained via longitudinal observational data. Methods: We considered six drug families that are commonly assoc...

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Bibliographic Details
Main Authors:	Reps, Jenna M., Aickelin, Uwe, Hubbard, Richard B.
Format:	Article
Published:	Elsevier 2016
Online Access:	https://eprints.nottingham.ac.uk/34048/

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