Activation of constitutive androstane receptor (CAR) in primary human hepatocytes

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Activation of constitutive androstane receptor (CAR) in primary human hepatocytes

Human populations are at risk of exposure to constitutive androstane receptor (CAR) activators present in a range of substances, including pharmaceuticals, plasticizers and crop protection agents. What exposure to CAR activators means for human health is uncertain. Activation of CAR in rodents is as...

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Bibliographic Details
Main Author:	Maclennan, Richard Alexander
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Subjects:	Liver hepatocyte agrochemical toxicity constitutive androstane receptor proliferation human hepatocyte
Online Access:	https://eprints.nottingham.ac.uk/33726/

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