SmokeHaz: systematic reviews and meta-analyses of the effects of smoking on respiratory health
Background: Smoking tobacco increases the risk of respiratory disease in adults and children, but communicating the magnitude of these effects in a scientific manner that is accessible and usable by public and policymakers presents a challenge. We have therefore summarised scientific data on the imp...
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| Format: | Article |
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Elsevier
2016
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| Online Access: | https://eprints.nottingham.ac.uk/33435/ |
| _version_ | 1848794630593708032 |
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| author | Jayes, Leah Haslam, Patricia L. Gratziou, Christina G. Powell, Pippa Britton, John Vardavas, Constantine Jimenez-Ruiz, Carlos Leonardi-Bee, Jo |
| author_facet | Jayes, Leah Haslam, Patricia L. Gratziou, Christina G. Powell, Pippa Britton, John Vardavas, Constantine Jimenez-Ruiz, Carlos Leonardi-Bee, Jo |
| author_sort | Jayes, Leah |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Background: Smoking tobacco increases the risk of respiratory disease in adults and children, but communicating the magnitude of these effects in a scientific manner that is accessible and usable by public and policymakers presents a challenge. We have therefore summarised scientific data on the impact of smoking on respiratory diseases to provide the content for a unique resource, SmokeHaz.
Methods: We conducted systematic reviews and meta-analyses of longitudinal studies (published to 2013) identified from electronic databases, grey literature, and experts. Random effect meta-analyses were used to pool the findings.
Results: We included 216 papers. Among adult smokers, we confirmed substantially increased risks of lung cancer (Risk Ratio (RR) 10.92, 95% CI 8.28-14.40; 34 studies), COPD (RR 4.01, 95% CI 3.18-5.05; 22 studies) and asthma (RR 1.61, 95% CI 1.07-2.42; 8 studies). Exposure to passive smoke significantly increased the risk of lung cancer in adult non-smokers; and increased the risks of asthma, wheeze, lower respiratory infections, and reduced lung function in children. Smoking significantly increased the risk of sleep apnoea, and asthma exacerbations in adult and pregnant populations; and active and passive smoking increased the risk of tuberculosis.
Conclusions: These findings have been translated into easily digestible content and published on the SmokeHaz website (www.smokehaz.eu). |
| first_indexed | 2025-11-14T19:19:15Z |
| format | Article |
| id | nottingham-33435 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:19:15Z |
| publishDate | 2016 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-334352020-05-04T20:02:08Z https://eprints.nottingham.ac.uk/33435/ SmokeHaz: systematic reviews and meta-analyses of the effects of smoking on respiratory health Jayes, Leah Haslam, Patricia L. Gratziou, Christina G. Powell, Pippa Britton, John Vardavas, Constantine Jimenez-Ruiz, Carlos Leonardi-Bee, Jo Background: Smoking tobacco increases the risk of respiratory disease in adults and children, but communicating the magnitude of these effects in a scientific manner that is accessible and usable by public and policymakers presents a challenge. We have therefore summarised scientific data on the impact of smoking on respiratory diseases to provide the content for a unique resource, SmokeHaz. Methods: We conducted systematic reviews and meta-analyses of longitudinal studies (published to 2013) identified from electronic databases, grey literature, and experts. Random effect meta-analyses were used to pool the findings. Results: We included 216 papers. Among adult smokers, we confirmed substantially increased risks of lung cancer (Risk Ratio (RR) 10.92, 95% CI 8.28-14.40; 34 studies), COPD (RR 4.01, 95% CI 3.18-5.05; 22 studies) and asthma (RR 1.61, 95% CI 1.07-2.42; 8 studies). Exposure to passive smoke significantly increased the risk of lung cancer in adult non-smokers; and increased the risks of asthma, wheeze, lower respiratory infections, and reduced lung function in children. Smoking significantly increased the risk of sleep apnoea, and asthma exacerbations in adult and pregnant populations; and active and passive smoking increased the risk of tuberculosis. Conclusions: These findings have been translated into easily digestible content and published on the SmokeHaz website (www.smokehaz.eu). Elsevier 2016-07 Article PeerReviewed Jayes, Leah, Haslam, Patricia L., Gratziou, Christina G., Powell, Pippa, Britton, John, Vardavas, Constantine, Jimenez-Ruiz, Carlos and Leonardi-Bee, Jo (2016) SmokeHaz: systematic reviews and meta-analyses of the effects of smoking on respiratory health. Chest, 150 (1). pp. 164-179. ISSN 1931-3543 Smoking Passive Smoking Systematic Review Meta-Analysis Respiratory Diseases Lung Diseases Health Risks Policy Makers Public Awareness http://www.sciencedirect.com/science/article/pii/S0012369216485478 doi:10.1016/j.chest.2016.03.060 doi:10.1016/j.chest.2016.03.060 |
| spellingShingle | Smoking Passive Smoking Systematic Review Meta-Analysis Respiratory Diseases Lung Diseases Health Risks Policy Makers Public Awareness Jayes, Leah Haslam, Patricia L. Gratziou, Christina G. Powell, Pippa Britton, John Vardavas, Constantine Jimenez-Ruiz, Carlos Leonardi-Bee, Jo SmokeHaz: systematic reviews and meta-analyses of the effects of smoking on respiratory health |
| title | SmokeHaz: systematic reviews and meta-analyses of the effects of smoking on respiratory health |
| title_full | SmokeHaz: systematic reviews and meta-analyses of the effects of smoking on respiratory health |
| title_fullStr | SmokeHaz: systematic reviews and meta-analyses of the effects of smoking on respiratory health |
| title_full_unstemmed | SmokeHaz: systematic reviews and meta-analyses of the effects of smoking on respiratory health |
| title_short | SmokeHaz: systematic reviews and meta-analyses of the effects of smoking on respiratory health |
| title_sort | smokehaz: systematic reviews and meta-analyses of the effects of smoking on respiratory health |
| topic | Smoking Passive Smoking Systematic Review Meta-Analysis Respiratory Diseases Lung Diseases Health Risks Policy Makers Public Awareness |
| url | https://eprints.nottingham.ac.uk/33435/ https://eprints.nottingham.ac.uk/33435/ https://eprints.nottingham.ac.uk/33435/ |