Attributes for causal inference in electronic healthcare databases

Side effects of prescription drugs present a serious issue. Existing algorithms that detect side effects generally require further analysis to confirm causality. In this paper we investigate attributes based on the Bradford-Hill causality criteria that could be used by a classifying algorithm to...

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Main Authors: Reps, Jenna, Garibaldi, Jonathan M., Aickelin, Uwe, Soria, Daniele, Gibson, Jack E., Hubbard, Richard B.
Format: Conference or Workshop Item
Published: 2013
Subjects:
Online Access:https://eprints.nottingham.ac.uk/3342/
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author Reps, Jenna
Garibaldi, Jonathan M.
Aickelin, Uwe
Soria, Daniele
Gibson, Jack E.
Hubbard, Richard B.
author_facet Reps, Jenna
Garibaldi, Jonathan M.
Aickelin, Uwe
Soria, Daniele
Gibson, Jack E.
Hubbard, Richard B.
author_sort Reps, Jenna
building Nottingham Research Data Repository
collection Online Access
description Side effects of prescription drugs present a serious issue. Existing algorithms that detect side effects generally require further analysis to confirm causality. In this paper we investigate attributes based on the Bradford-Hill causality criteria that could be used by a classifying algorithm to definitively identify side effects directly. We found that it would be advantageous to use attributes based on the association strength, temporality and specificity criteria.
first_indexed 2025-11-14T18:21:37Z
format Conference or Workshop Item
id nottingham-3342
institution University of Nottingham Malaysia Campus
institution_category Local University
last_indexed 2025-11-14T18:21:37Z
publishDate 2013
recordtype eprints
repository_type Digital Repository
spelling nottingham-33422020-05-04T20:20:50Z https://eprints.nottingham.ac.uk/3342/ Attributes for causal inference in electronic healthcare databases Reps, Jenna Garibaldi, Jonathan M. Aickelin, Uwe Soria, Daniele Gibson, Jack E. Hubbard, Richard B. Side effects of prescription drugs present a serious issue. Existing algorithms that detect side effects generally require further analysis to confirm causality. In this paper we investigate attributes based on the Bradford-Hill causality criteria that could be used by a classifying algorithm to definitively identify side effects directly. We found that it would be advantageous to use attributes based on the association strength, temporality and specificity criteria. 2013 Conference or Workshop Item PeerReviewed Reps, Jenna, Garibaldi, Jonathan M., Aickelin, Uwe, Soria, Daniele, Gibson, Jack E. and Hubbard, Richard B. (2013) Attributes for causal inference in electronic healthcare databases. In: CBMS 2013, The 26th IEEE International Symposium on Computer-Based Medical Systems, Porto, 20-22 June 2013, Porto, Portugal. Biomedical Informatics Data Mining http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6627871
spellingShingle Biomedical Informatics
Data Mining
Reps, Jenna
Garibaldi, Jonathan M.
Aickelin, Uwe
Soria, Daniele
Gibson, Jack E.
Hubbard, Richard B.
Attributes for causal inference in electronic healthcare databases
title Attributes for causal inference in electronic healthcare databases
title_full Attributes for causal inference in electronic healthcare databases
title_fullStr Attributes for causal inference in electronic healthcare databases
title_full_unstemmed Attributes for causal inference in electronic healthcare databases
title_short Attributes for causal inference in electronic healthcare databases
title_sort attributes for causal inference in electronic healthcare databases
topic Biomedical Informatics
Data Mining
url https://eprints.nottingham.ac.uk/3342/
https://eprints.nottingham.ac.uk/3342/