An investigation of druggable prognostic markers in paediatric ependymoma

QR Code

An investigation of druggable prognostic markers in paediatric ependymoma

Background: Paediatric ependymomas are the second most common malignant brain tumours in children. Tumour recurrence, chemoresistance and invasion of surrounding critical structures are the hallmarks of ependymomas. These features are consistent with the cancer stem cell (CSC) hypothesis which state...

Full description

Bibliographic Details
Main Author:	Sabnis, Durgagauri
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2016
Subjects:	Ependymoma ABCB1 BLBP MGMT
Online Access:	https://eprints.nottingham.ac.uk/33243/

Similar Items

An investigation of metastatic markers in models of paediatric medulloblastoma
by: Nasir, Aishah
Published: (2017)

Transcriptomic analysis in pediatric spinal ependymoma reveals distinct molecular signatures
by: Lourdusamy, Anbarasu, et al.
Published: (2017)

Integrating transcriptomics and metabolomics to analyse and target tumour heterogeneity in paediatric ependymoma
by: Pandele, Alina Gabriela
Published: (2024)

Recurrent paediatric ependymoma: a multicentre analysis of clinical features and tumour biology in the molecular era
by: Ritzmann, Timothy
Published: (2018)

Expression alterations define unique molecular characteristics of spinal ependymomas
by: Lourdusamy, Anbarasu, et al.
Published: (2015)

Recommendations for assessing cognitive risks in young children treated for ependymoma for clinical and research protocols: evidence from a systematic literature review
by: Morrall, Matthew C.H.J., et al.
Published: (2014)

microRNA network analysis identifies miR-29 cluster as key regulator of LAMA2 in ependymoma
by: Lourdusamy, Anbarasu, et al.
Published: (2015)

Investigating the role the PI3K pathway plays in ependymoma pathogenesis
by: Estranero, Jasper
Published: (2019)

Medulloblastoma and ependymoma cells display levels of 5-carboxylcytosine and elevated TET1 expression
by: Ramsawhook, Ashley, et al.
Published: (2017)

Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas
by: Pajtler, Kristian W., et al.
Published: (2018)

Long-term exposure to irinotecan reduces cell migration in glioma cells.
by: Al-Ghafari, Ayat B., et al.
Published: (2016)

Expressions of P-glycoprotein in treatment: Resistant Helicobacter pylori patients
by: Omar, Marhanis, et al.
Published: (2014)

Exploring the role of multidrug exporters and extracellular vesicles in medulloblastoma chemoresistance
by: Wade, Philippa
Published: (2024)

The role of p-glycoprotein in bacterial attachment to intestinal cells.
by: Crowe, Andrew
Published: (2010)

Genomic and epigenetic characterisation of childhood ependymoma
by: Kilday, John-Paul
Published: (2011)

Determination Of Prognostic Markers For Cervical Cancer
by: Ahmad, Rahmatul Wahida
Published: (2008)

Wilms' Tumor protein 1 and enzymatic oxidation of 5-methylcytosine in brain tumors: potential perspectives
by: Ramsawhook, Ashley, et al.
Published: (2018)

Translating childhood brain tumour research into clinical practice: the experience of molecular classification and diagnostics
by: Ritzmann, Timothy A., et al.
Published: (2018)

Prognostic Markers Of Resistance And Relapse In Acute Leukaemia
by: Pon, Maha Abdullah@Maha-Lakswmi
Published: (2003)

Less utilized prognostic markers in acute myeloid leukaemia
by: Abdullah, Maha
Published: (2016)

In vivo effects of sirolimus and sunitinib of breast cancer prognostic markers
by: Jaffar, Nurul Fathiyatul Nabila
Published: (2020)

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
by: Wain, Louise V., et al.
Published: (2017)

A hybrid prognostic model for oral cancer based on clinicopathologic and genomic markers
by: Siow, Wee Chang, et al.
Published: (2014)

Hedgehog signalling molecule, SMO is a poor prognostic marker in bladder cancer
by: Mohd Ariffin, Khairunnisa, et al.
Published: (2021)

Unveiling a novel transient druggable pocket in BACE-1 through molecular simulations: conformational analysis and binding mode of multisite inhibitors
by: Di Pietro, Ornella, et al.
Published: (2017)

In silico identification and characterization of potential druggable targets among hypothetical proteins of Leptospira interrogans serovar Copenhageni: a comprehensive bioinformatics approach
by: Siddiqui, Quratulain, et al.
Published: (2022)

Rankl expression as a prognostic marker in stage III giant cell tumour of the bone
by: Abdul Ghani , Nur Sabrina
Published: (2015)

CD105 (Endoglin) exerts prognostic effects via its role in the microvascular niche of paediatric high grade glioma
by: Smith, Stuart J., et al.
Published: (2012)

B-type natriuretic peptide trumps other prognostic markers in patients assessed for coronary disease
by: Kotecha, D., et al.
Published: (2019)

Identification of an eight-LncRNA signature as the prognostic LncRNA markers in hepatocellular carcinoma patients
by: Li, Sixu, et al.
Published: (2022)

Co-infections of hepatitis B patients with other hepatitis viruses and their serological, biological and prognostic markers
by: Hudu Abdullahi, Shuaibu
Published: (2017)

The prognostic value of the stem-like group in colorectal cancer using a panel of immunohistochemistry markers
by: Ong, C., et al.
Published: (2015)

CD26: A prognostic marker of acute lymphoblastic leukemia in children in the post remission induction phase
by: Mende, Atheer Awad, et al.
Published: (2015)

Amino acid transporters in breast cancer: promising prognostic markers and emerging targets across molecular subtypes
by: El Ansari, Rokaya
Published: (2020)

Long pentraxin PTX3 as a prognostic marker of cardiovascular mortality in patients with chronic kidney disease
by: Baragetti, A., et al.
Published: (2017)

Survival rate and prognostic factors of Ewing Family Tumor in paediatric patients (a 11-year review) in Hospital USM from 2002-2012
by: Adenam, Norhaila Mohamad
Published: (2016)

LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia
by: Kaderi, Mohd Arifin
Published: (2011)

Gene expression analysis of heat-shock proteins and redox regulators reveals combinatorial prognostic markers in carcinomas of the gastrointestinal tract
by: Pohl, S., et al.
Published: (2018)

Paediatric tracheostomy
by: Asha'ari, Zamzil Amin
Published: (2015)

Paediatric Nutrition
by: Binns, Colin, et al.
Published: (2014)